Background: Chronic pain is a major health issue, adversely affecting millions of Australians
and costing billions of dollars annually. Current pharmaceutical treatments may be limiting …

Although used therapeutically for millennia, cannabis has been a prohibited substance
worldwide for most of the 20th Century. With revision of prohibitive regulations in many …

There is a growing body of evidence to support the use of medical cannabis as an adjunct to
or substitute for prescription opiates in the treatment of chronic pain. When used in …

Setting. Cannabis preparations have been used as a remedy for thousands of years in
traditional medicine. Clinical use of cannabinoid substances is restricted, due to legal and …

Advances in cannabis research have paralleled developments in opioid pharmacology
whereby a psychoactive plant extract has elucidated novel endogenous signalling systems …

Abstract Knowledge about the therapeutic potential of medical cannabis has greatly
improved over the past decade, with an ever-increasing range of developments in human …

Headache disorders are common, debilitating, and, in many cases, inadequately managed
by existing treatments. Although clinical trials of cannabis for neuropathic pain have shown …

Abstract Purpose of Review Cannabis has been used since ancient times for medical and
recreational research. This review article will document the validity of how medical cannabis …

Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

The most important discoveries in pharmacology, such as certain classes of analgesics or
chemotherapeutics, started from natural extracts which have been found to have effects in …