Quantification of glutathione transverse relaxation time T2 using echo time extension with variable refocusing selectivity and symmetry in the human brain at 7 Tesla
KM Swanberg, H Prinsen, D Coman… - Journal of Magnetic …, 2018 - Elsevier
Glutathione (GSH) is an endogenous antioxidant implicated in numerous biological
processes, including those associated with multiple sclerosis, aging, and cancer. Spectral …
processes, including those associated with multiple sclerosis, aging, and cancer. Spectral …
Glutamate and glutamine: a review of in vivo MRS in the human brain
Our understanding of the roles that the amino acids glutamate (Glu) and glutamine (Gln)
play in the mammalian central nervous system has increased rapidly in recent times. Many …
play in the mammalian central nervous system has increased rapidly in recent times. Many …
Spectral simplification for resolved glutamate and glutamine measurement using a standard STEAM sequence with optimized timing parameters at 3, 4, 4.7, 7, and 9.4 …
The C4 multiplet proton resonances of glutamate (Glu) around 2.35 ppm and glutamine
(Gln) around 2.45 ppm usually overlap in MR spectra, particularly at low‐and mid‐field …
(Gln) around 2.45 ppm usually overlap in MR spectra, particularly at low‐and mid‐field …
1H MRS detection of glycine residue of reduced glutathione in vivo
LG Kaiser, M Marjańska, GB Matson, I Iltis… - Journal of Magnetic …, 2010 - Elsevier
Glutathione (GSH) is a powerful antioxidant found inside different kinds of cells, including
those of the central nervous system. Detection of GSH in the human brain using 1H MR …
those of the central nervous system. Detection of GSH in the human brain using 1H MR …
Detection of glutamate/glutamine resonances by 1H magnetic resonance spectroscopy at 0.5 tesla
RW Prost, L Mark, M Mewissen… - Magnetic resonance in …, 1997 - Wiley Online Library
Midfield proton magnetic resonance spectroscopy (MRS) provides a noninvasive method to
monitor glutamate and glutamine (Glx) levels in vivo. Experiments to detect the γ and β …
monitor glutamate and glutamine (Glx) levels in vivo. Experiments to detect the γ and β …
An in vivo proton magnetic resonance spectroscopy study with optimized echo-time technique for concurrent quantification and T2 measurement targeting glutamate …
Objective The present study applied in vivo proton magnetic resonance spectroscopy (1 H
MRS) to concurrently measure the concentration and T2 relaxation time of glutamate with …
MRS) to concurrently measure the concentration and T2 relaxation time of glutamate with …
Dynamic observation of 2H labeled compounds in the human brain with 1H versus 2H magnetic resonance spectroscopy at 9.4T
L Ruhm, T Ziegs, AM Wright, CS Mathy… - bioRxiv, 2022 - biorxiv.org
Abstract The metabolic pathway of [6, 6'-2H2]-labeled glucose was investigated with two
different techniques. The first technique used direct detection of deuterium applying …
different techniques. The first technique used direct detection of deuterium applying …
Simultaneous editing of GABA and glutathione at 7T using semi‐LASER localization
Purpose To demonstrate simultaneous editing of the two most commonly edited and
overlapping signals, γ‐aminobutyric acid (GABA), and glutathione (GSH), with Hadamard …
overlapping signals, γ‐aminobutyric acid (GABA), and glutathione (GSH), with Hadamard …
Simultaneous quantification of glutamate and glutamine by J‐modulated spectroscopy at 3 Tesla
Y Zhang, J Shen - Magnetic resonance in medicine, 2016 - Wiley Online Library
Purpose The echo time (TE) averaged spectrum is the one‐dimensional (1D) cross‐section
of the J‐resolved spectrum at J= 0. In multiecho TE‐averaged spectroscopy, glutamate (Glu) …
of the J‐resolved spectrum at J= 0. In multiecho TE‐averaged spectroscopy, glutamate (Glu) …