Invasive aspergillosis is characterized by hyphal invasion of the blood vessels, which
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus …

Invasive aspergillosis is characterized by two different types of angioinvasion. During
pulmonary aspergillosis, hyphae are initially outside of the pulmonary vasculature and they …

Hyphal invasion of blood vessels is a prominent feature of invasive aspergillosis. During
invasive pulmonary aspergillosis, Aspergillus fumigatus hyphae invade the abluminal …

Invasive aspergillosis causes significant mortality among patients with hematologic
malignancies. This infection is characterized by vascular invasion and thrombosis. To study …

Aspergillus fumigatus is an important opportunistic fungal pathogen that can cause acute
invasive disease in neutropenic hosts. Invasive aspergillosis is being diagnosed with …

Many fungi that cause invasive disease invade host epithelial cells during mucosal and
respiratory infection, and subsequently invade endothelial cells during hematogenous …

Background The airway epithelium is the first barrier interacting with Aspergillus fumigatus
conidia after their inhalation, suggesting that this structure functions as point of entry of this …

Monocytes play a major role in the cellular defence against Aspergillus fumigatus in
immunocompromised patients. To obtain a better understanding of the mechanisms …

In invasive pulmonary aspergillosis, direct invasion and occlusion of pulmonary vasculature
by Aspergillus hyphae causes tissue hypoxia, which is enhanced by secreted fungal …

Background. Little is known about the pathogenesis of invasive pulmonary aspergillosis and
the relationship between the kinetics of diagnostic markers and the outcome of antifungal …