Synthesis and biological evaluation of 4-amino-5-cinnamoylthiazoles as chalcone-like anticancer agents
A Ayati, R Esmaeili, S Moghimi, TO Bakhshaiesh… - European journal of …, 2018 - Elsevier
Abstract A series of 4-amino-5-cinnamoylthiazoles 3a-p were designed and synthesized as
chalcone-like anticancer agents. The synthesized derivatives 3a-p were evaluated for their …
chalcone-like anticancer agents. The synthesized derivatives 3a-p were evaluated for their …
Anticancer activity of novel 3‐(furan‐2‐yl) pyrazolyl and 3‐(thiophen‐2‐yl) pyrazolyl hybrid chalcones: Synthesis and in vitro studies
MT Helmy, FM Sroor, KF Mahrous… - Archiv der …, 2022 - Wiley Online Library
Twelve novel chalcone derivatives were prepared using the Claisen–Schmidt condensation
reaction. The reaction of 4‐acetyl‐5‐furan/thiophene‐pyrazole derivatives 5 with the …
reaction. The reaction of 4‐acetyl‐5‐furan/thiophene‐pyrazole derivatives 5 with the …
Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity
TA Farghaly, GS Masaret, ZA Muhammad… - Bioorganic chemistry, 2020 - Elsevier
The crucial need for novel antitumor agents with high selectivity toward cancer cells has
promoted us to synthesize new series of thiazole-based chalcones and 4-hetarylthiazoles …
promoted us to synthesize new series of thiazole-based chalcones and 4-hetarylthiazoles …
Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4, 5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor …
Novel (E)-1-aryl-3-(3-aryl-1-phenyl-1H-pyrazol-4-yl) prop-2-en-1-ones 5/6 (pyrazolic
chalcones) were synthesized from a Claisen–Schmidt reaction of 3-aryl-1-phenylpyrazol-4 …
chalcones) were synthesized from a Claisen–Schmidt reaction of 3-aryl-1-phenylpyrazol-4 …
Heterocycles 26: synthesis, characterisation, and anticancer activity of some thiazolic chalcones
Chalcones and their derivatives have been shown to have potent anticancer activity. A
series of aldehydes A 1–4 and thiazolic chalcones C 1–20 were synthesized and evaluated …
series of aldehydes A 1–4 and thiazolic chalcones C 1–20 were synthesized and evaluated …
Synthesis of thiazole linked chalcones and their pyrimidine analogues as anticancer agents
C Kesari, KR Rama, K Sedighi, J Stenvang… - Synthetic …, 2021 - Taylor & Francis
A series of nine novel thiazole linked chalcones,(E)-3-(4-methyl-2-(4 (trifluoromethyl)
phenyl) thiazol-5-yl)-1-phenylprop-2-en-1-one derivatives 7–15 were synthesized. To …
phenyl) thiazol-5-yl)-1-phenylprop-2-en-1-one derivatives 7–15 were synthesized. To …
Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents
A series of substituted chalcones and their corresponding pyrazoles were synthesized and
evaluated for in vitro cytotoxic activity against a panel of human cancer cell lines. Out of 93 …
evaluated for in vitro cytotoxic activity against a panel of human cancer cell lines. Out of 93 …
Synthesis and anti-proliferative activity of a novel 1, 2, 3-triazole tethered chalcone acetamide derivatives
S Vanaparthi, R Bantu, N Jain, S Janardhan… - Bioorganic & Medicinal …, 2020 - Elsevier
Abstract A new series of 1, 2, 3-triazole tethered chalcone acetamide derivatives (7a-c & 8a-
r) have been synthesized in excellent yields and their structures were determined by …
r) have been synthesized in excellent yields and their structures were determined by …
Anticancer Activity of New Bis-(3-(Thiophen-2-yl)-1H-Pyrazol-4-yl)Chalcones: Synthesis, in-Silico, and in-Vitro Studies
FM Sroor, MF Mohamed, GK Abdullah… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A series of bis-chalcones with alkyl linkers incorporating 3-(thiophen-2-yl) pyrazole 5–10
has been prepared by the condensation reaction of two moles of 3-(thiophen-2-yl) pyrazole …
has been prepared by the condensation reaction of two moles of 3-(thiophen-2-yl) pyrazole …
Synthesis and antitumor-evaluation of 1, 3-selenazole-containing 1, 3, 4-thiadiazole derivatives
HC Zhao, YP Shi, YM Liu, CW Li, LN Xuan… - Bioorganic & medicinal …, 2013 - Elsevier
Abstract A series of novel 1, 3-selenazole-containing 1, 3, 4-thiadiazole derivatives bearing
Schiff base moieties were synthesized and evaluated for their in vitro antiproliferative …
Schiff base moieties were synthesized and evaluated for their in vitro antiproliferative …