Aerosol delivery devices in the treatment of asthma

DR Hess - Respiratory care, 2008 - rc.rcjournal.com
Nebulizers convert solutions or suspensions into aerosols with a particle size that can be
inhaled into the lower respiratory tract. There are pneumatic jet nebulizers, ultrasonic …

Aerosol devices and asthma therapy

W Berger - Current drug delivery, 2009 - ingentaconnect.com
Aerosol delivery of asthma medications maximizes local effects in the lung and minimizes
systemic effects compared with oral therapy. Both corticosteroids and bronchodilators are …

Device selection and outcomes of aerosol therapy: evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and …

MB Dolovich, RC Ahrens, DR Hess, P Anderson… - Chest, 2005 - Elsevier
Background The proliferation of inhaler devices has resulted in a confusing number of
choices for clinicians who are selecting a delivery device for aerosol therapy. There are …

Lung dose, distribution, and clinical response to therapeutic aerosols

M Dolovich - Aerosol science and technology, 1993 - Taylor & Francis
The response to therapeutic aerosols is considered to be a function of the dose deposited at
the target site in the lung. The dose, in turn, is dependent upon the system producing the …

Delivery options and devices for aerosolized therapeutics

PJ Anderson - Chest, 2001 - Elsevier
Although inhalation is one of the oldest modes of drug delivery, it is currently receiving
renewed attention. Prior to 1987, aerosolized therapeutics were delivered via systems that …

The challenge of delivering therapeutic aerosols to asthma patients

F Lavorini - International Scholarly Research Notices, 2013 - Wiley Online Library
The number of people with asthma continues to grow around the world, and asthma remains
a poorly controlled disease despite the availability of management guidelines and highly …

Aerosol deposition considerations in inhalation therapy

SP Newman - Chest, 1985 - Elsevier
Successful aerosol therapy generally depends on the small percentage (typically 10
percent) of the drug dose delivered to the lungs from metered-dose inhalers (MDIs) …

Current therapies and technological advances in aqueous aerosol drug delivery

AB Watts, JT McConville… - Drug development and …, 2008 - Taylor & Francis
Recent advances in aerosolization technology have led to renewed interest in pulmonary
delivery of a variety of drugs. Pressurized metered dose inhalers (pMDIs) and dry powder …

Inhalation therapy: technological milestones in asthma treatment

R Dalby, J Suman - Advanced drug delivery reviews, 2003 - Elsevier
The humble origins of the propellant driven metered dose inhaler, as a response to a child's
enquiry, initiated an industry which supplies approximately a half billion inhalers globally for …

Devices for improved delivery of nebulized pharmaceutical aerosols to the lungs

W Longest, B Spence, M Hindle - Journal of aerosol medicine and …, 2019 - liebertpub.com
Nebulizers have a number of advantages for the delivery of inhaled pharmaceutical
aerosols, including the use of aqueous formulations and the ability to deliver process …