[HTML][HTML] Coenzyme Q10 ameliorates the quality of postovulatory aged oocytes by suppressing DNA damage and apoptosis

M Zhang, X ShiYang, Y Zhang, Y Miao, Y Chen… - Free Radical Biology …, 2019 - Elsevier
Postovulatory aging is known to compromise the oocyte quality as well as subsequent
embryo development in many different animal models, and becomes one of the most …

Melatonin protects oocyte quality from Bisphenol A‐induced deterioration in the mouse

M Zhang, X Dai, Y Lu, Y Miao, C Zhou… - Journal of Pineal …, 2017 - Wiley Online Library
Bisphenol A (BPA) has been reported to adversely affect the mammalian reproductive
system in both sexes. However, the underlying mechanisms regarding how BPA disrupts the …

Roles of resveratrol in improving the quality of postovulatory aging oocytes in vitro

YL Sun, SB Tang, W Shen, S Yin, QY Sun - Cells, 2019 - mdpi.com
After ovulation, mammalian oocytes will undergo a time-dependent process of aging if they
are not fertilized. This postovulatory aging (POA) seriously affects the oocyte quality and …

Melatonin reduces oxidative damage in mouse granulosa cells via restraining JNK-dependent autophagy

Y Cao, M Shen, Y Jiang, S Sun, H Liu - Reproduction, 2018 - rep.bioscientifica.com
Oxidative stress-induced granulosa cell (GCs) injury is believed to be a common trigger for
follicular atresia. Emerging evidence indicates that excessive autophagy occurs in …

Mitochondrial dysfunction and ovarian aging

I Kasapoğlu, E Seli - Endocrinology, 2020 - academic.oup.com
As women delay childbearing because of demographic and socioeconomic trends,
reproductive aging and ensuing ovarian dysfunction become increasingly more prevalent …

Melatonin improves the meiotic maturation of porcine oocytes by reducing endoplasmic reticulum stress during in vitro maturation

HJ Park, JY Park, JW Kim, SG Yang… - Journal of pineal …, 2018 - Wiley Online Library
Under endoplasmic reticulum (ER)‐stress conditions, the unfolded protein response (UPR)
generates a defense mechanism in mammalian cells. The regulation of UPR signaling is …

[HTML][HTML] Melatonin and the circadian system: contributions to successful female reproduction

RJ Reiter, H Tamura, DX Tan, XY Xu - Fertility and sterility, 2014 - Elsevier
Objective To summarize the role of melatonin and circadian rhythms in determining optimal
female reproductive physiology, especially at the peripheral level. Design Databases were …

[HTML][HTML] Melatonin inhibits oxidative stress and apoptosis in cryopreserved ovarian tissues via Nrf2/HO-1 signaling pathway

TC Sun, XC Liu, SH Yang, LL Song, SJ Zhou… - Frontiers in Molecular …, 2020 - frontiersin.org
In the field of assisted reproductive technology, female fertility preservation, particularly
ovarian tissue cryopreservation in adolescent cancer patients, has attracted much attention …

Reproductive longevity and aging: geroscience approaches to maintain long-term ovarian fitness

N Llarena, C Hine - The Journals of Gerontology: Series A, 2021 - academic.oup.com
Increases in delayed childbearing worldwide have elicited the need for a better
understanding of the biological underpinnings and implications of age-related infertility. In …

Melatonin improves the quality of inferior bovine oocytes and promoted their subsequent IVF embryo development: mechanisms and results

M Yang, J Tao, M Chai, H Wu, J Wang, G Li, C He… - Molecules, 2017 - mdpi.com
The inferior oocytes (IOs), which are not suitable for embryo development, occupy roughly
one-third or more of the collected immature bovine oocytes. The IOs are usually discarded …