Review of safety and efficacy of sleep medicines in older adults

JL Schroeck, J Ford, EL Conway, KE Kurtzhalts… - Clinical …, 2016 - Elsevier
Purpose Insomnia is problematic for older adults. After behavioral modifications fail to show
adequate response, pharmacologic options are used. The pharmacokinetics of agents used …

Insomnia in elderly patients: recommendations for pharmacological management

VC Abad, C Guilleminault - Drugs & aging, 2018 - Springer
Chronic insomnia affects 57% of the elderly in the United States, with impairment of quality
of life, function, and health. Chronic insomnia burdens society with billions of dollars in direct …

Management of chronic insomnia in elderly persons

KT Bain - The American journal of geriatric pharmacotherapy, 2006 - Elsevier
BACKGROUND:: Chronic insomnia is common among the elderly These elderly patients are
often viewed as difficult to treat, yet they are among the groups with the greatest need of …

Sleep in the elderly: burden, diagnosis, and treatment

WV McCall - Prim Care Companion J Clin Psychiatry, 2004 - legacy.psychiatrist.com
Insomnia is commonly seen in elderly populations and is associated with numerous
individual and socioeconomic consequences. Elderly patients are more likely to suffer from …

Efficacy and safety of non-benzodiazepine and non-Z-drug hypnotic medication for insomnia in older people: a systematic literature review

J Sys, S Van Cleynenbreugel, M Deschodt… - European Journal of …, 2020 - Springer
Purpose Insomnia is highly prevalent in older persons and significantly impacts quality of
life, functional abilities, and health status. It is frequently treated with benzodiazepines or Z …

Insomnia in the elderly: a review

D Patel, J Steinberg, P Patel - Journal of Clinical Sleep Medicine, 2018 - jcsm.aasm.org
Background: Insomnia remains one of the most common sleep disorders encountered in the
geriatric clinic population, frequently characterized by the subjective complaint of difficulty …

Sleep maintenance insomnia: strengths and weaknesses of current pharmacologic therapies

RP Rosenberg - Annals of Clinical Psychiatry, 2006 - Taylor & Francis
Background. Although insomnia is highly prevalent, sleep disturbances often go
unrecognized and untreated. When insomnia is recognized, considerable emphasis has …

Drugs for insomnia beyond benzodiazepines: pharmacology, clinical applications, and discovery

T Atkin, S Comai, G Gobbi - Pharmacological reviews, 2018 - ASPET
Although the GABAergic benzodiazepines (BZDs) and Z-drugs (zolpidem, zopiclone, and
zaleplon) are FDA-approved for insomnia disorders with a strong evidence base, they have …

Insomnia: pharmacologic therapy

E Matheson, BL Hainer - American family physician, 2017 - aafp.org
Insomnia accounts for more than 5.5 million visits to family physicians each year. Although
behavioral interventions are the mainstay of treatment, pharmacologic therapy may be …

Drugs for insomnia

N Zisapel - Expert opinion on emerging drugs, 2012 - Taylor & Francis
Introduction: Sleep is a vital neurochemical process involving sleep-promoting and arousal
centers in the brain. Insomnia is a pervasive disorder characterized by difficulties in initiating …