Recent progress and future directions of the research on nanoplastic-induced neurotoxicity

SW Han, J Choi, KY Ryu - Neural regeneration research, 2024 - journals.lww.com
Many types of plastic products, including polystyrene, have long been used in commercial
and industrial applications. Microplastics and nanoplastics, plastic particles derived from …

Polystyrene nano-and microplastic particles induce an inflammatory gene expression profile in rat neural stem cell-derived astrocytes in vitro

KA Marcellus, S Bugiel, A Nunnikhoven, I Curran… - Nanomaterials, 2024 - mdpi.com
Microplastics are considered an emerging environmental pollutant due to their ubiquitous
presence in the environment. However, the potential impact of microplastics on human …

The plastic brain: neurotoxicity of micro-and nanoplastics

M Prüst, J Meijer, RHS Westerink - Particle and fibre toxicology, 2020 - Springer
Given the global abundance and environmental persistence, exposure of humans and
(aquatic) animals to micro-and nanoplastics is unavoidable. Current evidence indicates that …

Neurotoxicities induced by micro/nanoplastics: A review focusing on the risks of neurological diseases

S Liu, Y He, J Yin, Q Zhu, C Liao, G Jiang - Journal of Hazardous Materials, 2024 - Elsevier
Pollution of micro/nano-plastics (MPs/NPs) is ubiquitously prevalent in the environment,
leading to an unavoidable exposure of the human body. Despite the protection of the blood …

Neurotoxic potential of polystyrene nanoplastics in primary cells originating from mouse brain

BK Jung, SW Han, SH Park, JS Bae, J Choi, KY Ryu - Neurotoxicology, 2020 - Elsevier
Polystyrene (PS) and chemically modified compounds in the PS family have long been used
in commercial and industrial fields. However, it is poorly understood whether nanoscale-PS …

Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice

S Shan, Y Zhang, H Zhao, T Zeng, X Zhao - Chemosphere, 2022 - Elsevier
Microplastics (MPs) have been well demonstrated as potential threats to the ecosystem,
whereas the neurotoxicity of MPs in mammals remains to be elucidated. The current study …

Brain single-nucleus transcriptomics highlights that polystyrene nanoplastics potentially induce Parkinson's disease-like neurodegeneration by causing energy …

B Liang, Y Huang, Y Zhong, Z Li, R Ye, B Wang… - Journal of Hazardous …, 2022 - Elsevier
With the prevalence of nanoplastics in daily life, human exposure is inevitable. However,
whether and how nanoplastics cause neurotoxicity in humans remains obscure. Herein, we …

Stress response of mouse embryonic fibroblasts exposed to polystyrene nanoplastics

SW Han, J Choi, KY Ryu - International journal of molecular sciences, 2021 - mdpi.com
Polystyrene (PS) nanoplastic exposure has been shown to affect the viability of neuronal
cells isolated from mouse embryonic brains. However, the viability of mouse embryonic …

Maternal exposure to polystyrene nanoplastics causes brain abnormalities in progeny

B Jeong, JY Baek, J Koo, S Park, YK Ryu… - Journal of Hazardous …, 2022 - Elsevier
As global plastic production continues to grow, microplastics released from a massive
quantity of plastic wastes have become a critical environmental concern. These microplastic …

Internalization and toxicity of polystyrene nanoplastics on inmortalized human neural stem cells

MC González-Caballero, M de Alba González… - Chemosphere, 2024 - Elsevier
Global plastic production has increased exponentially in recent decades, and a significant
part of it persists in the environment, where it degrades into microplastics and nanoplastics …