Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

S Monti, KJ Savage, JL Kutok, F Feuerhake, P Kurtin… - Blood, 2005 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with recognized
variability in clinical outcome, genetic features, and cells of origin. To date, transcriptional …

Diagnosis of 'double hit'diffuse large B-cell lymphoma and B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and Burkitt lymphoma: when …

SH Swerdlow - Hematology 2014, the American Society of …, 2014 - ashpublications.org
Identification of large B-cell lymphomas that are “extra-aggressive” and may require therapy
other than that used for diffuse large B-cell lymphoma, not otherwise specified (DLBCL …

Prognostic impact of immunohistochemically defined germinal center phenotype in diffuse large B-cell lymphoma patients treated with immunochemotherapy

H Nyman, M Adde… - Blood, The Journal …, 2007 - ashpublications.org
Germinal center (GC) and non-GC phenotypes are predictors of outcome in diffuse large B-
cell lymphoma (DLBCL) and can be used to stratify chemotherapy-treated patients into low …

The t (14; 18) is associated with germinal center-derived diffuse large B-cell lymphoma and is a strong predictor of outcome

SL Barrans, PAS Evans, SJM O'Connor, SJ Kendall… - Clinical cancer …, 2003 - AACR
Abstract The t (14; 18) is present in a significant proportion of diffuse large B-cell lymphomas
(DLBCLs), however, the prognostic effect of the translocation and the relationship with …

[HTML][HTML] Prognostic factors for diffuse large B-cell lymphoma in the R (X) CHOP era

R Vaidya, TE Witzig - Annals of oncology, 2014 - Elsevier
Background The introduction of rituximab (R) to conventional CHOP chemotherapy for newly
diagnosed diffuse large B-cell lymphoma (DLBCL) led to an unequivocal improvement in …

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

JG Lohr, P Stojanov, MS Lawrence… - Proceedings of the …, 2012 - National Acad Sciences
To gain insight into the genomic basis of diffuse large B-cell lymphoma (DLBCL), we
performed massively parallel whole-exome sequencing of 55 primary tumor samples from …

[HTML][HTML] Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma

MCJ Ma, S Tadros, A Bouska, T Heavican, H Yang… - …, 2022 - ncbi.nlm.nih.gov
B-cell non-Hodgkin lymphoma (B-NHL) encompasses multiple clinically and phenotypically
distinct subtypes of malignancy with unique molecular etiologies. Common subtypes of B …

Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas

IS Lossos, AA Alizadeh, MB Eisen… - Proceedings of the …, 2000 - National Acad Sciences
B cell diffuse large cell lymphoma (B-DLCL) is a heterogeneous group of tumors, based on
significant variations in morphology, clinical presentation, and response to treatment. Gene …

Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas

MJ Kluk, B Chapuy, P Sinha, A Roy, PD Cin… - PloS one, 2012 - journals.plos.org
Diffuse large B cell lymphoma (DLBCL) is a clinically and genetically heterogeneous
disease. A small subset of DLBCLs has translocations involving the MYC locus and an …

Genetic landscapes of relapsed and refractory diffuse large B-cell lymphomas

RD Morin, S Assouline, M Alcaide, A Mohajeri… - Clinical cancer …, 2016 - AACR
Purpose: Relapsed or refractory diffuse large B-cell lymphoma (rrDLBCL) is fatal in 90% of
patients, and yet little is known about its biology. Experimental Design: Using exome …