[HTML][HTML] Novel nano-drug delivery system for brain tumor treatment

Z Qiu, Z Yu, T Xu, L Wang, N Meng, H Jin, B Xu - Cells, 2022 - mdpi.com
As the most dangerous tumors, brain tumors are usually treated with surgical removal,
radiation therapy, and chemotherapy. However, due to the aggressive growth of gliomas …

Micro‐nanocarriers based drug delivery technology for blood‐brain barrier crossing and brain tumor targeting therapy

L Wang, Y Shi, J Jiang, C Li, H Zhang, X Zhang… - Small, 2022 - Wiley Online Library
The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …

Advances in targeted drug delivery approaches for the central nervous system tumors: the inspiration of nanobiotechnology

J Meng, V Agrahari, I Youm - Journal of Neuroimmune Pharmacology, 2017 - Springer
At present, brain tumor is among the most challenging diseases to treat and the therapy is
limited by the lack of effective methods to deliver anticancer agents across the blood-brain …

Strategies to overcome/penetrate the BBB for systemic nanoparticle delivery to the brain/brain tumor

HJ Liu, P Xu - Advanced drug delivery reviews, 2022 - Elsevier
Despite its prevalence in the management of peripheral tumors, compared to surgery and
radiation therapy, chemotherapy is still a suboptimal intervention in fighting against brain …

Recent advances in brain tumor-targeted nano-drug delivery systems

Y Liu, W Lu - Expert opinion on drug delivery, 2012 - Taylor & Francis
Introduction: Brain tumors represent one of the most challenging and difficult areas in unmet
medical needs. Fortunately, the past decade has seen momentous developments in brain …

[HTML][HTML] Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

Beyond the blood–brain barrier: facing new challenges and prospects of nanotechnology-mediated targeted delivery to the brain

M Kumar, P Sharma, R Maheshwari, M Tekade… - … -Based Targeted Drug …, 2018 - Elsevier
The blood–brain barrier (BBB) is a stealth barrier that protects the brain, and allows the entry
of only a select pool of compounds into the brain and functions towards the maintenance of …

Nanocarriers for the treatment of glioblastoma multiforme: current state-of-the-art

R Karim, C Palazzo, B Evrard, G Piel - Journal of controlled release, 2016 - Elsevier
Glioblastoma multiforme, a grade IV glioma, is the most frequently occurring and invasive
primary tumor of the central nervous system, which causes about 4% of cancer-associated …

Recent advances in drug delivery systems for targeting brain tumors

Y Zhao, P Yue, Y Peng, Y Sun, X Chen, Z Zhao… - Drug delivery, 2023 - Taylor & Francis
Brain tumor accounts for about 1.6% of incidence and 2.5% of mortality of all tumors, and the
median survival for brain tumor patients is only about 20 months. The treatment for brain …

[HTML][HTML] Targeting to brain tumor: Nanocarrier-based drug delivery platforms, opportunities, and challenges

LA Kumar, G Pattnaik, BS Satapathy… - Journal of Pharmacy …, 2021 - journals.lww.com
Cancer is a class of disorder characterized by anomalous growth of cells escalating in an
uncontrolled way. Among all the cancers, treatment of cancerous brain tumors has been a …