Implications of gut microbiota dysbiosis and fecal metabolite changes in psychologically stressed mice

Y Zhang, J Zhang, J Wu, Q Zhu, C Chen… - Frontiers in microbiology, 2023 - frontiersin.org
Introduction Psychological stress can induce affective disorders. Gut microbiota plays a vital
role in emotional function regulation; however, the association between gut microbiota and …

[HTML][HTML] Gut microbiota-brain axis modulation by a healthier microbiological microenvironment: facts and fictions

UC Ghoshal - Journal of Neurogastroenterology and Motility, 2018 - ncbi.nlm.nih.gov
Vol. 24, No. 1 January, 2018 (4-6) with probiotics reduced the development of these effects.
5, 7 Moreover, the role of gut microbiota in causing these pathophysiological effects was …

Stress in the microbiome-immune crosstalk

E Beurel - Gut Microbes, 2024 - Taylor & Francis
The gut microbiota exerts a mutualistic interaction with the host in a fragile ecosystem and
the host intestinal, neural, and immune cells. Perturbations of the gastrointestinal track …

High-fat diet and antibiotics cooperatively impair mitochondrial bioenergetics to trigger dysbiosis that exacerbates pre-inflammatory bowel disease

JY Lee, SA Cevallos, MX Byndloss, CR Tiffany… - Cell host & …, 2020 - cell.com
The clinical spectra of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD)
intersect to form a scantily defined overlap syndrome, termed pre-IBD. We show that …

Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease

E Urbauer, D Aguanno, N Mindermann, H Omer… - bioRxiv, 2023 - biorxiv.org
Mitochondrial dysfunction in intestinal epithelial cells (IECs) is associated with chronic
inflammation. To understand how microbial-metabolic circuits contribute to tissue injury, we …

Post-stress changes in the gut microbiome composition in rats with different levels of nervous system excitability

A Shevchenko, I Shalaginova, D Katserov, L Matskova… - PloS One, 2023 - journals.plos.org
The gut-brain axis is a critical communication system influencing the interactions between
the gastrointestinal tract (GI) and the central nervous system (CNS). The gut microbiota plays …

Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3

W Hao, Q Ma, L Wang, N Yuan, H Gan, L He, X Li… - Microbiome, 2024 - Springer
Background Remodeling eubiosis of the gut microenvironment may contribute to preventing
the occurrence and development of depression. Mounting experimental evidence has …

Chronic Stress Induced Gut Microbial Dysbiosis Disturbs Vitamin B6 Metabolism and Results in Abnormal Behaviors in Rats

W Qing, H Chen, X Ma, J Chen, Y Le, H Chen… - Available at SSRN … - papers.ssrn.com
Background: Chronic stress related consequences including psychological diseases and
neurodegenerative diseases are healthy challenge globally. This study aimed to explore …

Stress-induced obesity in mice causes cognitive decline associated with inhibition of hippocampal neurogenesis and dysfunctional gut microbiota

J Zhang, YE Liu, Z Zhao, H He, L Li, C Xiao, T Zhou… - Frontiers in … - frontiersin.org
1. Chronic stress can induce diet-independent obesity in mice. 2. Stress-induced obesity
involves alterations in the gut microbiome and hyperactivation of the hypothalamic-pituitary …

Of bowels, brain and behavior: a role for the gut microbiota in psychiatric comorbidities in irritable bowel syndrome

L Wilmes, JM Collins, KJ O'Riordan… - …, 2021 - Wiley Online Library
Background The gastrointestinal microbiota has emerged as a key regulator of gut‐brain
axis signalling with important implications for neurogastroenterology. There is continuous …