Background Understanding the mechanisms underpinning the response to acute stress is
critical for determining how this can be modulated in both health and disease and across …

A role of the mitochondrial dynamin-related protein (Drp1) on gut microbiome composition
and intestinal barrier function after hemorrhagic shock has not been identified previously …

The intestinal microbiota has been reported to affect depression, a common mental
condition with severe health‐related consequences. However, what mediates the effect of …

Psychological stress can trigger inflammatory bowel disease (IBD) flares, but the molecular
mechanisms have remained unclear. We recently discovered an unexpected function of the …

Bacterial colonisation of the intestine has a major role in the post-natal development and
maturation of the immune and endocrine systems. These processes are key factors …

Background Intestinal homeostasis is a dynamic process that takes place at the interface
between the lumen and the mucosa of the gastrointestinal tract, where a constant scrutiny for …

Stress is one of the major causes of irritable bowel syndrome (IBS), which is well-known for
perturbing the microbiome and exacerbating IBS-associated symptoms. However, changes …

Increasing evidence suggests the involvement of neuroinflammatory pathways and gut
microbiota in major depressive disorder and in antidepressant response. Inflammasome …

Emerging evidence supports the gut microbiota and the brain communication in general
health. This axis may affect behavior through modulating neurotransmission, and thereby …