[HTML][HTML] Gut microbiota changes require vagus nerve integrity to promote depressive-like behaviors in mice

E Siopi, M Galerne, M Rivagorda, S Saha… - Molecular …, 2023 - nature.com
Chronic stress constitutes a major risk factor for depression that can disrupt various aspects
of homeostasis, including the gut microbiome (GM). We have recently shown that GM …

Gut–brain axis: how the microbiome influences anxiety and depression

JA Foster, KAMV Neufeld - Trends in neurosciences, 2013 - cell.com
Within the first few days of life, humans are colonized by commensal intestinal microbiota.
Here, we review recent findings showing that microbiota are important in normal healthy …

The microbiota-gut-brain axis: from motility to mood

KG Margolis, JF Cryan, EA Mayer - Gastroenterology, 2021 - Elsevier
The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

[HTML][HTML] Enteric microbiota-mediated serotonergic signaling in pathogenesis of irritable bowel syndrome

Y Mishima, S Ishihara - International Journal of Molecular Sciences, 2021 - mdpi.com
Irritable bowel syndrome (IBS) is a chronic functional disorder that affects the gastrointestinal
tract. Details regarding the pathogenesis of IBS remain largely unknown, though the …

[HTML][HTML] Analysis of brain networks and fecal metabolites reveals brain–gut alterations in premenopausal females with irritable bowel syndrome

V Osadchiy, EA Mayer, K Gao, JS Labus… - Translational …, 2020 - nature.com
Alterations in brain–gut–microbiome (BGM) interactions have been implicated in the
pathogenesis of irritable bowel syndrome (IBS). Here, we apply a systems biology approach …

[HTML][HTML] Mechanistic insights into the link between gut dysbiosis and major depression: an extensive review

S Sonali, B Ray, H Ahmed Tousif, AG Rathipriya… - Cells, 2022 - mdpi.com
Depression is a highly common mental disorder, which is often multifactorial with sex,
genetic, environmental, and/or psychological causes. Recent advancements in biomedical …

AhR/IL-22 pathway as new target for the treatment of post-infectious irritable bowel syndrome symptoms

M Meynier, E Baudu, N Rolhion, M Defaye… - Gut …, 2022 - Taylor & Francis
Alterations in brain/gut/microbiota axis are linked to Irritable Bowel Syndrome (IBS)
physiopathology. Upon gastrointestinal infection, chronic abdominal pain and anxio …

Mitochondrial dysfunction induced by HIF‐1α under hypoxia contributes to the development of gastric mucosal lesions

Y Xiao, X Liu, K Xie, J Luo, Y Zhang… - Clinical and …, 2024 - Wiley Online Library
Introduction Hypoxia is an important characteristic of gastric mucosal diseases, and hypoxia‐
inducible factor‐1α (HIF‐1α) contributes to microenvironment disturbance and metabolic …

Bidirectional gut‐microbial mediated‐brain signaling: A new player in stress physiology?(Commentary on O'Mahony et al., 2019)

M Fleshner - European Journal of Neuroscience, 2020 - Wiley Online Library
Commentary on O'Mahony SM, McVey Neufeld K‐A, Waworuntu RV, et al. The enduring
effects of early‐life stress on the microbiota–gut–brain axis are buffered by dietary …

[HTML][HTML] Changes in gut microbiota by chronic stress impair the efficacy of fluoxetine

E Siopi, G Chevalier, L Katsimpardi, S Saha, M Bigot… - Cell Reports, 2020 - cell.com
Major depressive disorders (MDDs) constitute a leading cause of disability worldwide and
current pharmacological treatments are partially effective. The gut microbiota (GM) has …