[PDF][PDF] AhR/IL-22 pathway as new target for the treatment of post-infectious irritable bowel syndrome symptoms

G Microbes - 2022 - uca.hal.science
Alterations in brain/gut/microbiota axis are linked to Irritable Bowel Syndrome (IBS)
physiopathology. Upon gastrointestinal infection, chronic abdominal pain and anxio …

Mitochondrial perturbation of the epithelium causes microbial dysbiosis and unresolved tissue injury in intestinal inflammation

E Urbauer, D Aguanno, N Mindermann, H Omer… - 2023 - europepmc.org
Mitochondrial dysfunction in intestinal epithelial cells (IECs) is associated with chronic
inflammation. To understand how microbial-metabolic circuits contribute to tissue injury, we …

Link Stress-Related Gut Microbiota Shifts to Mental Health Outcomes

AA Madison, MT Bailey - Biological Psychiatry, 2023 - Elsevier
Stress levels are surging, alongside the incidence of stress-related psychiatric disorders.
Perhaps a related phenomenon, especially in urban areas, the human gut contains fewer …

Effect of chronic restraint stress and western‐diet feeding on colonic regulatory gene expression in mice

KM Hatton‐Jones, EF du Toit… - Neurogastroenterology & …, 2022 - Wiley Online Library
Background Diet‐induced obesity (DIO) and psychological stress are significant
independent regulators of gastrointestinal physiology; however, our understanding of how …

[HTML][HTML] Stress & the gut-brain axis: regulation by the microbiome

JA Foster, L Rinaman, JF Cryan - Neurobiology of stress, 2017 - Elsevier
The importance of the gut–brain axis in regulating stress-related responses has long been
appreciated. More recently, the microbiota has emerged as a key player in the control of this …

[HTML][HTML] Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

JR Kelly, PJ Kennedy, JF Cryan, TG Dinan… - Frontiers in cellular …, 2015 - frontiersin.org
The emerging links between our gut microbiome and the central nervous system are
regarded as a paradigm shift in neuroscience with possible implications for not only …

[HTML][HTML] Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease

SL Wang, BZ Shao, SB Zhao, X Chang, P Wang… - Cell death & …, 2019 - nature.com
Psychosocial stress is a critical inducing factor of inflammatory bowel diseases (IBD), while
autophagy is a novel central issue of IBD development. The present study investigated the …

Chronic Stress-Induced Depression and Anxiety Priming Modulated by Gut-Brain-Axis Immunity

G Pasinetti, S Westfall - Current Developments in Nutrition, 2022 - Elsevier
Objectives: Chronic stress manifests as depressive-and anxiety-like behavior while recurrent
stress elicits disproportionate psychiatric responses linked to stress-induced immunological …

[HTML][HTML] The impact of microbiota on the gut–brain axis: Examining the complex interplay and implications

TS Chaudhry, SG Senapati, S Gadam… - Journal of clinical …, 2023 - mdpi.com
The association and interaction between the central nervous system (CNS) and enteric
nervous system (ENS) is well established. Essentially ENS is the second brain, as we call it …

The impact of acute and chronic stress on gastrointestinal physiology and function: a microbiota–gut–brain axis perspective

SJ Leigh, F Uhlig, L Wilmes… - The Journal of …, 2023 - Wiley Online Library
The physiological consequences of stress often manifest in the gastrointestinal tract.
Traumatic or chronic stress is associated with widespread maladaptive changes throughout …