Butterflies in the gut: the interplay between intestinal microbiota and stress

TT Lai, CW Liou, YH Tsai, YY Lin, WL Wu - Journal of biomedical science, 2023 - Springer
Psychological stress is a global issue that affects at least one-third of the population
worldwide and increases the risk of numerous psychiatric disorders. Accumulating evidence …

Integrated fecal microbiome–metabolome signatures reflect stress and serotonin metabolism in irritable bowel syndrome

Z Mujagic, M Kasapi, DMAE Jonkers, I Garcia-Perez… - Gut …, 2022 - Taylor & Francis
To gain insight into the complex microbiome-gut-brain axis in irritable bowel syndrome (IBS),
several modalities of biological and clinical data must be combined. We aimed to identify …

Systematical comparison reveals distinct brain transcriptomic features in models of depression induced by gut microbiota dysbiosis and chronic stress

S Gui, Y Liu, J Pu, D Wang, X Zhong, W Chen, X Chen… - 2024 - researchsquare.com
Major depressive disorder (MDD) is a devastating psychiatric illness caused by various
etiologies. Both chronic stress and gut microbiome dysbiosis are implicated in the …

Signalling cognition: the gut microbiota and hypothalamic-pituitary-adrenal axis

JA Rusch, BT Layden, LR Dugas - Frontiers in endocrinology, 2023 - frontiersin.org
Cognitive function in humans depends on the complex and interplay between multiple body
systems, including the hypothalamic-pituitary-adrenal (HPA) axis. The gut microbiota, which …

The microbiota drives diurnal rhythms in tryptophan metabolism in the stressed gut

CE Gheorghe, SJ Leigh, GSS Tofani… - Cell Reports, 2024 - cell.com
Chronic stress disrupts microbiota-gut-brain axis function and is associated with altered
tryptophan metabolism, impaired gut barrier function, and disrupted diurnal rhythms …

[HTML][HTML] Abnormalities in microbiota/butyrate/FFAR3 signaling in aging gut impair brain function

SP Mishra, S Jain, B Wang, S Wang, BC Miller, JY Lee… - JCI insight, 2024 - ncbi.nlm.nih.gov
Aging-related abnormalities in gut microbiota are associated with cognitive decline,
depression, and anxiety, but underlying mechanisms remain unstudied. Here, our study …

[引用][C] Enteric nervous system transfers stress to the gut

I Fyfe - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
The enteric nervous system (ENS) has a central role in the exacerbation of inflammatory
bowel disease (IBD) by psychological stress, according to research published in Cell. The …

Gut microbiota requires vagus nerve integrity to promote depression

E Siopi, S Saha, C Moigneu, M Bigot, PM Lledo - bioRxiv, 2019 - biorxiv.org
Chronic stress constitutes one of the strongest risk factors for depression and can disrupt
various aspects of homeostasis, including gut microbiota composition. We found that stress …

Chronic psychological stress disrupted the composition of the murine colonic microbiota and accelerated a murine model of inflammatory bowel disease

Y Watanabe, S Arase, N Nagaoka, M Kawai… - PloS one, 2016 - journals.plos.org
The effect of psychological stress on the gastrointestinal microbiota is widely recognized.
Chronic psychological stress may be associated with increased disease activity in …

Integrated analysis of the microbiota-gut-brain axis in response to sleep deprivation and diet-induced obesity

J Lee, J Kang, Y Kim, S Lee, CM Oh… - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction Sleep deprivation (SD) and obesity are common in modern societies. SD and
obesity frequently coexist, but research on the combined consequences of SD and obesity …