Focal therapy in prostate cancer: modalities, findings and future considerations

U Lindner, J Trachtenberg, N Lawrentschuk - Nature Reviews Urology, 2010 - nature.com
Focal therapy is emerging as an alternative to active surveillance for the management of low-
risk prostate cancer in carefully selected patients. The aim of focal therapy is long-term …

An update on focal therapy for prostate cancer

M Perera, N Krishnananthan, U Lindner… - Nature Reviews …, 2016 - nature.com
Globally, the increased uptake of serum PSA level screening led to an increase in the
number of diagnoses of low-risk and intermediate-risk prostate cancer. Traditionally, these …

Focal therapy in the management of prostate cancer: an emerging approach for localized prostate cancer

T Nomura, H Mimata - Advances in urology, 2012 - Wiley Online Library
A widespread screening with prostate‐specific antigen (PSA) has led increased diagnosis of
localized prostate cancer along with a reduction in the proportion of advanced‐stage …

[HTML][HTML] Focal therapy for prostate cancer: rationale and treatment opportunities

V Kasivisvanathan, M Emberton, HU Ahmed - Clinical Oncology, 2013 - Elsevier
Focal therapy is an emerging treatment modality for localised prostate cancer that aims to
reduce the morbidity seen with radical therapy, while maintaining cancer control. Focal …

Focal therapy for localized prostate cancer: a critical appraisal of rationale and modalities

SE Eggener, PT Scardino, PR Carroll, MJ Zelefsky… - The Journal of …, 2007 - Elsevier
PURPOSE: Based on contemporary epidemiological and pathological characteristics of
prostate cancer we explain the rationale for and concerns about focal therapy for low risk …

New technologies and techniques for prostate cancer focal therapy.

E Linares-Espinos, A Carneiro… - Minerva urologica e …, 2018 - europepmc.org
INTRODUCTION: The aim of this study was to review the oncological and functional
outcomes of new and established primary focal treatments (FT) for localized prostate cancer …

Conceptual basis for focal therapy in prostate cancer

E Lecornet, HU Ahmed, CM Moore… - Journal of …, 2010 - liebertpub.com
The proportion of men with low-to intermediate-risk prostate cancer is rising with the
increasing use of formal and informal prostate-specific antigen screening. The risk-to-benefit …

Focal therapy in prostate cancer: international multidisciplinary consensus on trial design

W Van Den Bos, BG Muller, H Ahmed, CH Bangma… - European urology, 2014 - Elsevier
Background Focal therapy has been introduced for the treatment of localised prostate
cancer (PCa). To provide the necessary data for consistent assessment, all focal therapy …

Image guidance for focal therapy of prostate cancer

U Lindner, N Lawrentschuk, J Trachtenberg - World journal of urology, 2010 - Springer
Focal therapy is an appealing strategy for any tumor and in time may prove to be a valuable
treatment option for low-risk, carefully selected prostate cancer (PCa) patients. In an era …

Active surveillance and radical therapy in prostate cancer: can focal therapy offer the middle way?

HU Ahmed, M Emberton - World journal of urology, 2008 - Springer
Introduction Focal therapy for prostate cancer is a radical paradigm shift in the management
of men with localised prostate cancer. It involves locating and destroying only the areas of …