[HTML][HTML] A randomized phase II trial of single-agent gemcitabine, vinorelbine, or docetaxel in patients with advanced non-small cell lung cancer who have poor …

SS Leong, CK Toh, WT Lim, X Lin, SB Tan… - Journal of Thoracic …, 2007 - Elsevier
Background: Patients with poor performance status and/or are elderly are frequently
considered a compromised group at high risk of chemotherapy-related morbidities and less …

Meeting the chemotherapy needs of elderly and poor performance status patients with NSCLC

C Gridelli, J Hainsworth - Lung cancer, 2002 - Elsevier
Increasing interest in designing chemotherapy suitable for use in the elderly and in poor
performance status (PS) patients has led to clinical trials in advanced non-small cell lung …

Does chemotherapy have a role as palliative therapy for unfit or elderly patients with non-small-cell lung cancer?

C Gridelli - Lung Cancer, 2002 - Elsevier
Elderly patients and younger “unfit” patients with poor Eastern Cooperative Oncology Group
(ECOG) performance status (PS)(≥ 2) suffering from advanced non-small-cell lung cancer …

Gemcitabine and cisplatin in the treatment of elderly patients with advanced non-small cell lung cancer: impact of comorbidities on safety and efficacy outcome

L Moscetti, F Nelli, D Padalino, I Sperduti… - Journal of …, 2005 - Taylor & Francis
The aim of the study was to describe in detail the impact of aging and comorbidities on
safety and efficacy of gemcitabine-cisplatin in the subset of elderly with advanced NSCLC …

Weekly docetaxel versus docetaxel/gemcitabine in the treatment of elderly or poor performance status patients with advanced nonsmall cell lung cancer: a …

JD Hainsworth, DR Spigel, C Farley, DL Shipley… - Cancer, 2007 - Wiley Online Library
BACKGROUND. The aim of this study was to compare the efficacy of single‐agent weekly
docetaxel with the combination of docetaxel and gemcitabine in elderly and/or poor …

Combination treatment with weekly docetaxel and gemcitabine for advanced non–small-cell lung cancer in elderly patients and patients with poor performance status …

JD Hainsworth, JB Erland, JH Barton, DS Thompson… - Clinical Lung Cancer, 2003 - Elsevier
The purpose of this study was to evaluate the feasibility, toxicity, and efficacy of the
combination of weekly docetaxel and gemcitabine in patients with advanced non–small-cell …

Biweekly administration of docetaxel and gemcitabine for elderly patients with advanced non-small cell lung cancer: a phase II study

KN Syrigos, E Karapanagiotou, A Charpidou… - Journal of …, 2007 - Taylor & Francis
With 69 years being the median age at diagnosis in the United States, management of
elderly patients with advanced non-small cell lung cancer (NSCLC) has become a common …

Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized …

C Gridelli, F Perrone, C Gallo, S Cigolari… - Journal of the …, 2003 - academic.oup.com
Background: Vinorelbine prolongs survival and improves quality of life in elderly patients
with advanced non-small-cell lung cancer (NSCLC). Some studies have also suggested that …

Gemcitabine plus vinorelbine in nonsmall cell lung carcinoma patients age 70 years or older or patients who cannot receive cisplatin

J Feliu, L López Gómez, C Madroñal, E Espinosa… - Cancer, 1999 - Wiley Online Library
BACKGROUND Although the prevalence of nonsmall cell lung carcinoma (NSCLC) is high
among elderly patients, few data are available regarding the efficacy and toxicity of …

Activity and toxicity of gemcitabine and gemcitabine+ vinorelbine in advanced non-small-cell lung cancer elderly patients: Phase II data from the Multicenter Italian …

C Gridelli, S Cigolari, C Gallo, L Manzione… - Lung Cancer, 2001 - Elsevier
Background: Following the demonstration that vinorelbine improves survival and quality of
life compared with best supportive care in elderly patients with advanced non-small-cell lung …