Diffusion‐weighted spin‐echo fMRI at 9.4 T: microvascular/tissue contribution to BOLD signal changes

SP Lee, AC Silva, K Ugurbil… - Magnetic Resonance in …, 1999 - Wiley Online Library
The nature of vascular contribution to blood oxygenation level dependent (BOLD) contrast
used in functional MRI (fMRI) is poorly understood. To investigate vascular contributions at …

Cortical depth‐dependent gradient‐echo and spin‐echo BOLD fMRI at 9.4 T

F Zhao, P Wang, SG Kim - … in Medicine: An Official Journal of …, 2004 - Wiley Online Library
To examine cortical depth‐related spatial specificity and signal changes in gradient‐echo
(GE) and spin‐echo (SE) blood oxygenation level‐dependent (BOLD) fMRI signals, a well …

Quantitative differentiation between BOLD models in fMRI

FGC Hoogenraad, PJW Pouwels… - … in Medicine: An …, 2001 - Wiley Online Library
Several gradient‐echo fMRI blood oxygenation level‐dependent (BOLD) effects are
described in the literature: extravascular spin dephasing around capillaries and veins …

Experimental measurement of extravascular parenchymal BOLD effects and tissue oxygen extraction fractions using multi‐echo VASO fMRI at 1.5 and 3.0 T

H Lu, PCM Van Zijl - … in Medicine: An Official Journal of the …, 2005 - Wiley Online Library
Quantitative interpretation of BOLD fMRI signal changes has predominantly employed
empirical models for the whole parenchyma and a calibration step is usually needed to …

Microvascular BOLD contribution at 4 and 7 T in the human brain: gradient‐echo and spin‐echo fMRI with suppression of blood effects

TQ Duong, E Yacoub, G Adriany, X Hu… - … in Medicine: An …, 2003 - Wiley Online Library
The BOLD signal consists of an intravascular (IV) and an extravascular (EV) component from
both small and large vessels. Their relative contributions are dependent on field strength …

Comparison of diffusion‐weighted high‐resolution CBF and spin‐echo BOLD fMRI at 9.4 T

SP Lee, AC Silva, SG Kim - … in Medicine: An Official Journal of …, 2002 - Wiley Online Library
The quantification of blood oxygenation‐level dependent (BOLD) functional MRI (fMRI)
signals is closely related to cerebral blood flow (CBF) change; therefore, understanding the …

Quantifying the intra‐and extravascular contributions to spin‐echo fMRI at 3 T

TH Jochimsen, DG Norris, T Mildner… - … in Medicine: An …, 2004 - Wiley Online Library
Functional MRI (fMRI) by means of spin‐echo (SE) techniques provides an interesting
alternative to gradient‐echo methods because the contrast is based primarily on dynamic …

The intravascular contribution to fmri signal change: monte carlo modeling and diffusion‐weighted studies in vivo

JL Boxerman, PA Bandettini, KK Kwong… - Magnetic resonance …, 1995 - Wiley Online Library
Understanding the relationship between fMRI signal changes and activated cortex is
paramount to successful mapping of neuronal activity. To this end, the relative extravascular …

Evidence for a vascular contribution to diffusion FMRI at high b value

KL Miller, DP Bulte, H Devlin… - Proceedings of the …, 2007 - National Acad Sciences
Recent work has suggested that diffusion-weighted functional magnetic resonance imaging
(FMRI) with strong diffusion weighting (high b value) detects neuronal swelling that is …

High‐resolution echo‐planar fMRI of human visual cortex at 3.0 tesla

KR Thulborn, SY Chang, GX Shen… - NMR in Biomedicine …, 1997 - Wiley Online Library
The robust detection of blood oxygenation level dependent (BOLD) contrast1, 2 that is due
to the hemodynamic response elicited by changes in neuronal activity is challenging. The …