Clefts of the lip and palate are a common craniofacial anomaly, requiring complex
multidisciplinary treatment and having lifelong implications for affected individuals. The …

Cleft lip with or without cleft palate is a common birth defect that is genetically complex. The
nonsyndromic forms have been studied genetically using linkage and candidate-gene …

Nonsyndromic cleft lip and/or palate (or orofacial cleft, OFC) is a malformation characterized
by an incomplete separation between nasal and oral cavities without any associated …

BACKGROUND Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common
birth defect with complex etiology reflecting the action of multiple genetic and environmental …

Clefts of the lip and palate (CLP), the major causes of congenital facial malformation
globally, result from failure of fusion of the facial processes during embryogenesis. With a …

Cleft lip and palate are common craniofacial deformities. The etiology underlying these
deformities is complex and multifactorial and they can occur as part of one of many …

Purpose We revisited 42 families with two or more cleft-affected siblings who participated in
previous studies. Complete dental information was collected to test the hypothesis that …

OBJECTIVE: To identify, in a non-hypothesis manner, novel genetic factors associated with
nonsyndromic cleft lip with or without cleft palate (NSCL/P). STUDY DESIGN: We performed …

Objective Although Asians have the highest birth prevalence of oral-facial clefts, the majority
of gene mapping studies of cleft lip with or without cleft palate (CL/P) have been in European …

Nonsyndromic oral clefts are among the most common birth defects, affecting approximately
1 in 1000 Caucasian newborns. In recent decades, many investigators have used genetic …