Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging

VJ Wedeen, P Hagmann, WYI Tseng… - Magnetic resonance …, 2005 - Wiley Online Library
Methods are presented to map complex fiber architectures in tissues by imaging the 3D
spectra of tissue water diffusion with MR. First, theoretical considerations show why and …

Understanding diffusion MR imaging techniques: from scalar diffusion-weighted imaging to diffusion tensor imaging and beyond

P Hagmann, L Jonasson, P Maeder, JP Thiran… - Radiographics, 2006 - pubs.rsna.org
The complex structural organization of the white matter of the brain can be depicted in vivo
in great detail with advanced diffusion magnetic resonance (MR) imaging schemes …

Diffusion MRI of complex tissue structure

DS Tuch - 2002 - dspace.mit.edu
Magnetic resonance diffusion imaging provides an exquisitely sensitive probe of tissue
microstructure. Owing to the microscopic length scale of diffusion in biological tissues …

MR imaging of anisotropically restricted diffusion of water in the nervous system: technical, anatomic, and pathologic considerations

JV Hajnal, M Doran, AS Hall, AG Collins… - Journal of computer …, 1991 - journals.lww.com
The use of MR imaging to image anisotropically restricted diffusion (ARD) of water in the
nervous system is described. The theoretical basis for the use of the pulsed gradient spin …

Diffusion MRI in the brain–Theory and concepts

JD Tournier - Progress in Nuclear Magnetic Resonance …, 2019 - Elsevier
Over the past two decades, diffusion MRI has become an essential tool in neuroimaging
investigations. This is due to its sensitivity to the motion of water molecules as they diffuse …

[HTML][HTML] Diffusion tensor imaging and beyond

JD Tournier, S Mori, A Leemans - Magnetic resonance in medicine, 2011 - ncbi.nlm.nih.gov
The diffusion of water molecules inside organic tissues is often anisotropic (1). Namely, if
there are aligned structures in the tissue, the apparent diffusion coefficient (ADC) of water …

[PDF][PDF] MR diffusion tensor spectroscopy and imaging

PJ Basser, J Mattiello, D LeBihan - Biophysical journal, 1994 - cell.com
This paper describes a new NMR imaging modality--MR diffusion tensor imaging. It consists
of estimating an effective diffusion tensor, Deff, within a voxel, and then displaying useful …

A general framework for experiment design in diffusion MRI and its application in measuring direct tissue‐microstructure features

DC Alexander - Magnetic Resonance in Medicine: An Official …, 2008 - Wiley Online Library
This article introduces a new and general framework for optimizing the experiment design
for diffusion MRI of samples with unknown orientation. An illustration then uses the …

The physical basis of diffusion-weighted MRI

M Cercignani, MA Horsfield - Journal of the neurological sciences, 2001 - Elsevier
Diffusion-weighted (DW) magnetic resonance imaging (MRI) is the only technique that
permits a non-invasive in vivo assessment of water molecular diffusion, which reflects tissue …

Diffusion magnetic resonance imaging: its principle and applications

S Mori, PB Barker - … Record: An Official Publication of the …, 1999 - Wiley Online Library
Diffusion magnetic resonance imaging (MRI) is one of the most rapidly evolving techniques
in the MRI field. This method exploits the random diffusional motion of water molecules …