Sorafenib is a multitarget tyrosine kinase inhibitor for the first-line treatment of hepatocellular
carcinoma (HCC). However, moderate therapeutic effects are common in the clinic …

Background: To prepare sorafenib-loaded folate-decorated bovine serum nanoparticles (FA-
SRF-BSANPs) and investigate their effect on the tumor targeting. Methods: The …

Chitosan nanoparticles (CS NPs) showed promising results in drug, vaccine and gene
delivery for the treatment of various diseases. The considerable attention towards CS was …

Sorafenib (SF) is an anticancer drug used to treat hepatocellular carcinoma (HCC), but it is
associated with a wide range of side effects. The objective of this research was to prepare …

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the
leading causes of cancer-related death worldwide. Advanced HCC displays strong …

The main aim of present study was to enhance the anticancer effect of sorafenib (SRF) in the
liver cancer cells. The SRF-loaded folate receptor-targeted polymer lipid hybrid nanoparticle …

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide.
Sorafenib (sfb) is widely used in clinics for advanced HCC therapy. However, the therapeutic …

Globally, one in six deaths is reported due to cancer suggesting the critical need for
development of advanced treatment regimens. In this study, solid lipid nanoparticles (SLN) …

Aim: Hybrids composed of various materials are highly versatile for drug delivery in tumor
therapy including hepatocellular carcinoma. Herein, a sorafenib (SF)-loaded …

Sorafenib is a molecularly targeted drug used for treating hepatocellular carcinoma.
However, sorafenib may affect the function of normal hepatocytes, and the clinical …