[HTML][HTML] Polymorphisms in the interleukin-1 (IL1) gene cluster are not associated with aggressive periodontitis in a large Caucasian population

A Fiebig, S Jepsen, BG Loos, C Scholz, C Schäfer… - Genomics, 2008 - Elsevier
Polymorphisms in the interleukin-1 (IL1) gene have been suggested to influence
transcription of IL1A (interleukin-1α) and IL1B (interleukin-1β) and thereby the …

Association between interleukin‐6 promoter haplotypes and aggressive periodontitis

L Nibali, GS Griffiths, N Donos, M Parkar… - Journal of clinical …, 2008 - Wiley Online Library
Abstract Background: Interleukin‐6 (IL‐6) polymorphisms have been shown to affect IL‐6
promoter activity. This study investigated the possible role of IL‐6 genetic polymorphisms …

Association between periodontitis and common variants in the promoter of the interleukin-6 gene

L Nibali, F D'aiuto, N Donos, GS Griffiths, M Parkar… - Cytokine, 2009 - Elsevier
We recently reported an association between interleukin-6 (IL6) polymorphisms (SNPs) and
haplotypes and aggressive periodontitis (AgP). The aim of this study was to investigate this …

[PDF][PDF] Interleukin-1 as a genetic marker for periodontitis: review of the literature

ME Grigoriadou, SO Koutayas… - Quintessence …, 2010 - researchgate.net
Periodontitis is considered to be a multifactorial disease. Studies have indicated that part of
the clinical variability in periodontitis may be explained by genetic factors. Genes can affect …

The association of interleukin‐4 haplotypes with chronic periodontitis in a Czech population

LI Holla, A Fassmann, P Augustin… - Journal of …, 2008 - Wiley Online Library
Background: Cytokine gene polymorphisms are known to influence the susceptibility and
disease course of many chronic disorders. Recently, interleukin (IL)‐4 gene polymorphisms …

Association of interleukin‐1 polymorphisms with aggressive periodontitis

L Quappe, L Jara, NJ López - Journal of Periodontology, 2004 - Wiley Online Library
Background: Genetic polymorphisms for interleukin (IL)‐1α and‐1β have been proposed as
potential genetic markers for periodontal diseases. Since the prevalence of these …

Association of interleukin‐1 polymorphisms with periodontal disease

NJ López, L Jara, CY Valenzuela - Journal of Periodontology, 2005 - Wiley Online Library
Background: Several studies have investigated genetic polymorphisms for cytokines as
potential genetic markers for periodontitis. Some studies have found that interleukin (IL)‐1A …

Polymorphisms within the IL‐1 gene cluster: Effects on cytokine profiles in peripheral blood and whole blood cell cultures of patients with aggressive periodontitis …

A Havemose‐Poulsen, LK Sørensen… - Journal of …, 2007 - Wiley Online Library
Background: Genetic polymorphisms of cytokines have been associated with the
susceptibility, severity, and clinical outcome of inflammatory diseases, such as periodontitis …

Comparison of interleukin‐1 genotypes in two populations with aggressive periodontitis

JR Gonzales, J Michel, EL Rodríguez… - European Journal of …, 2003 - Wiley Online Library
The genetic association of interleukin‐1 (IL‐1) with periodontitis has been investigated in
different populations. Failure to detect an association with IL‐1 genotypes in European …

Risk factors in adult periodontitis: polymorphism in the interleukin-1 gene family

ML Laine, MA Farre, MA Garcia-Gonzalez… - Nederlands Tijdschrift …, 2002 - europepmc.org
Interleukin (IL)-1 alpha, IL-1 beta and IL-1 receptor antagonist (ra) play a major role in
regulation of the inflammatory response in periodontal tissues. The aim of this study was to …