Glaucoma drugs in the pipeline

PL Kaufman, ME Mohr, SP Riccomini… - The Asia-Pacific …, 2018 - journals.lww.com
Glaucoma is a chronic disease that can be challenging to treat for both patients and
physicians. Most patients will require more than 1 medication over time to maintain their …

Exciting directions in glaucoma

CA Rasmussen, PL Kaufman - Canadian Journal of Ophthalmology, 2014 - Elsevier
Glaucoma is a complex, life-long disease that requires an individualized, multifaceted
approach to treatment. Most patients will be started on topical ocular hypotensive eyedrop …

[HTML][HTML] Focus: drug development: novel pharmacologic candidates for treatment of primary open-angle glaucoma

LJ Lu, JC Tsai, J Liu - The Yale Journal of Biology and Medicine, 2017 - ncbi.nlm.nih.gov
Primary open-angle glaucoma (OAG) affects approximately 45 million people worldwide and
more than 2.5 million people aged 40 years or older in the United States. Pharmacologic …

The latest drugs in development that reduce intraocular pressure in ocular hypertension and glaucoma

V Jayanetti, S Sandhu, JA Lusthaus - Journal of Experimental …, 2020 - Taylor & Francis
Glaucoma causes irreversible vision loss, with elevated intraocular pressure (IOP) being the
only known modifiable risk factor. There are a variety of medical and interventional options …

Emerging drugs for the treatment of glaucoma: a review of phase II & III trials

TM Kaplan, AJ Sit - Expert Opinion on Emerging Drugs, 2022 - Taylor & Francis
Introduction Glaucoma is a progressive optic neuropathy and the leading cause of
irreversible vision loss. By 2040, the number of individuals with glaucoma is expected to …

Glaucoma-next generation therapeutics: impossible to possible

CM Adams, R Stacy, N Rangaswamy, C Bigelow… - Pharmaceutical …, 2019 - Springer
The future of next generation therapeutics for glaucoma is strong. The recent approval of two
novel intraocular pressure (IOP)-lowering drugs with distinct mechanisms of action is the first …

Novel therapeutic approaches for glaucoma

CA Rasmussen, PL Kaufman - Drugs of the Future, 2011 - access.portico.org
Glaucoma refers to a collection of progressive optic neuropathies that can lead to
irreversible damage to retinal ganglion cells and their axons, and eventual loss of vision if …

Current and new pharmacotherapeutic approaches for glaucoma

WS Shalaby, V Shankar, R Razeghinejad… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Glaucoma is the leading cause of irreversible blindness worldwide. Medical
therapy is the main line of treatment of open-angle glaucoma (OAG) and ocular …

Medical treatment of glaucoma: present and future

P Fogagnolo, L Rossetti - Expert opinion on investigational drugs, 2011 - Taylor & Francis
Introduction: In the last decades, the therapy of glaucoma has largely shifted from surgery to
medical treatment thanks to the introduction of strongly effective formulations, that is …

New classes of glaucoma medications

EM Schehlein, GD Novack… - Current opinion in …, 2017 - journals.lww.com
Although challenges in medical treatment of glaucoma exist, particularly in patient
adherence, medical therapy remains the first line treatment for almost all glaucoma patients …