The role of angiogenesis in hepatocellular carcinoma

MA Morse, W Sun, R Kim, AR He, PB Abada… - Clinical Cancer …, 2019 - AACR
Hepatocellular carcinoma (HCC) accounts for about 90% of all primary liver cancers and is
the second leading cause of cancer-related deaths worldwide. The hypervascular nature of …

[HTML][HTML] Angiogenesis in hepatocellular carcinoma: mechanisms and anti-angiogenic therapies

C Yao, S Wu, J Kong, Y Sun, Y Bai, R Zhu… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-associated death
worldwide. Angiogenesis, the process of formation of new blood vessels, is required for …

Angiogenesis and antiangiogenic therapy in hepatocellular carcinoma

R Pang, RTP Poon - Cancer letters, 2006 - Elsevier
Hepatocellular carcinoma (HCC) is a hypervascular tumor characterized by
neovascularization, which plays an important role in the growth and progression of HCC …

Angiogenesis in hepatocellular carcinoma; pathophysiology, targeted therapy, and role of imaging

AW Moawad, J Szklaruk, C Lall, KJ Blair… - Journal of …, 2020 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the most common tumors worldwide, usually
occurring on a background of liver cirrhosis. HCC is a highly vascular tumor in which …

Vascular changes in hepatocellular carcinoma

ZF Yang, RTP Poon - The Anatomical Record: Advances in …, 2008 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most vascular solid tumors, in which
angiogenesis plays an important role. The status of angiogenesis in HCC correlates with the …

Angiogenesis in hepatocellular carcinoma: the retrospectives and perspectives

HC Sun, ZY Tang - Journal of cancer research and clinical oncology, 2004 - Springer
Hepatocellular carcinoma (HCC) is a typical hypervascular tumor. Many angiogenic factors
have been studied in HCC, and several anti-angiogenic therapies have been tested in …

HCC and angiogenesis: possible targets and future directions

AX Zhu, DG Duda, DV Sahani, RK Jain - Nature reviews Clinical …, 2011 - nature.com
Hepatocellular carcinoma (HCC), the most common primary liver tumor, is notoriously
resistant to systemic therapies, and often recurs even after aggressive local therapies. HCCs …

The mechanisms of angiogenesis in hepatocellular carcinoma: angiogenic switch during tumor progression

K Sugimachi, S Tanaka, T Terashi, K Taguchi… - Surgery, 2002 - Elsevier
Solid tumors constantly require a vascular supply for their progression and metastasis.
Hepatocellular carcinoma (HCC) is known to gain its hypervascularity during the process of …

Targeting angiogenesis in hepatocellular carcinoma: focus on VEGF and bevacizumab

RS Finn, AX Zhu - Expert review of anticancer therapy, 2009 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and
one of the few malignancies with an increasing incidence in the USA. While the relationship …

Angiogenesis inhibitors for the treatment of hepatocellular carcinoma

M Berretta, L Rinaldi, F Di Benedetto, A Lleshi… - Frontiers in …, 2016 - frontiersin.org
Background: Angiogenesis inhibitors have become an important therapeutic approach in the
treatment of hepatocellular carcinoma (HCC) patients. The therapeutic inhibition of …