Acetylcholinesterase is a critical enzyme that regulates neurotransmission by catalyzing the
breakdown of neurotransmitter acetylcholine in synapses of the nervous system. It is an …

Plant products have always been considered for many important metabolic disorders due to
its abundant medicinal properties. Alarming adverse effects of overuse of statins has been …

The angiotensin I-converting enzyme (ACE) has been found to exhibit inhibitory capability
against blood pressure. Recently, several ACE inhibitors with different structures have been …

Cholesteryl ester transfer protein (CETP), an enzyme which catalyses the transfer of
cholesteryl ester from HDL to VLDL, is a promising target for discovery of novel …

The two-domain dipeptidylcarboxypeptidase Angiotensin-I-converting enzyme (EC 3.4. 15.1;
ACE) plays an important physiological role in blood pressure regulation via the …

Inhibition of acetylcholinesterase (AChE) has been widely explored to develop novel
molecules for management of Alzheimer's disease. In past research finding reported …

Abstract Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR; EC 1.1. 1.34)
catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic …

Soluble epoxide hydrolase (sEH), a key enzyme belonging to cytochrome P450 pathway of
arachidonic acid cascade is a novel therapeutic drug target against atherosclerosis. The …

Inhibition of soluble epoxide hydrolase (sEH) is considered as an emerging druggable
target to reduce blood pressure, improve insulin sensitivity, and decrease inflammation …

Structural models have been generated for rat and human cholesterol esterases by
molecular modeling. For rat cholesterol esterase, three separate models were generated …