This review reflects a collaboration between the American Registry of Pathology (the
publisher of the Armed Forces Institute of Pathology Fascicles) and Annals of Diagnostic …

Context.—Lobular carcinoma in situ (LCIS) refers to a neoplastic proliferation of cells that
characteristically shows loss of E-cadherin expression and has long been regarded as a risk …

Lobular neoplasia (LN) is an atypical proliferation of small, dyscohesive epithelial cells
within the terminal duct lobular unit (TDLU), with or without pagetoid extension and …

Abstract Purpose of Review Lobular carcinoma in situ (LCIS) encompasses classical LCIS
and other rarer and more recently recognised variants, namely pleomorphic LCIS (PLCIS) …

Context.—Differentiating ductal carcinoma in situ (DCIS) from lobular carcinoma in situ
(LCIS) on core biopsy has important clinical implications. Lobular carcinoma in situ variants …

Lobular carcinoma in situ (LCIS) is considered a risk factor for development of invasive
carcinoma (IC). Many variants of LCIS have been described based on pathologic features …

Invasive lobular carcinoma (ILC) represents the second most common subtype of breast
cancer (BC), accounting for up to 15% of all invasive BC. Loss of cell adhesion due to …

Pleomorphic lobular carcinoma in situ (PLCIS) has only recently been identified as a distinct
pathological entity within classic lobular carcinoma in situ (CLCIS). As such, there is …

Background A diagnosis of non-classic lobular carcinoma in situ (NC-LCIS) encompasses a
variety of lesions with poorly characterized natural history. We evaluated upgrade rates and …

Background Lobular carcinoma in situ (LCIS) is considered a risk factor—not a precursor—
for both invasive lobular and ductal carcinoma. Florid LCIS (F-LCIS) is an architectural …