Kinetics of HCV envelope proteins' interaction with CD81 large extracellular loop
H Nakajima, L Cocquerel, N Kiyokawa… - Biochemical and …, 2005 - Elsevier
We used BIAcore to analyze the kinetics of interactions between CD81 and hepatitis C virus
(HCV) envelope proteins. We immobilized different forms of HCV envelope proteins (E1E2 …
(HCV) envelope proteins. We immobilized different forms of HCV envelope proteins (E1E2 …
CD81 is required for hepatitis C virus glycoprotein-mediated viral infection
ABSTRACT CD81 has been described as a putative receptor for hepatitis C virus (HCV);
however, its role in HCV cell entry has not been characterized due to the lack of an efficient …
however, its role in HCV cell entry has not been characterized due to the lack of an efficient …
Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I
SB Kapadia, H Barth, T Baumert, JA McKeating… - Journal of …, 2007 - Am Soc Microbiol
In the past several years, a number of cellular proteins have been identified as candidate
entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection …
entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection …
Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor
S Wünschmann, JD Medh, D Klinzmann… - Journal of …, 2000 - Am Soc Microbiol
Hepatitis C virus (HCV) or HCV–low-density lipoprotein (LDL) complexes interact with the
LDL receptor (LDLr) and the HCV envelope glycoprotein E2 interacts with CD81 in vitro …
LDL receptor (LDLr) and the HCV envelope glycoprotein E2 interacts with CD81 in vitro …
CD81-receptor associations—impact for hepatitis C virus entry and antiviral therapies
L Zona, RG Tawar, MB Zeisel, C Schuster, J Lupberger… - Viruses, 2014 - mdpi.com
Tetraspanins are integral transmembrane proteins organized in microdomains displaying
specific and direct interactions with other tetraspanins and molecular partners. Among them …
specific and direct interactions with other tetraspanins and molecular partners. Among them …
Serum-derived hepatitis C virus infection of primary human hepatocytes is tetraspanin CD81 dependent
S Molina, V Castet, L Pichard-Garcia… - Journal of …, 2008 - Am Soc Microbiol
Hepatitis C virus-positive serum (HCVser, genotypes 1a to 3a) or HCV cell culture
(JFH1/HCVcc) infection of primary normal human hepatocytes was assessed by measuring …
(JFH1/HCVcc) infection of primary normal human hepatocytes was assessed by measuring …
Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor
Several cell surface molecules have been proposed as receptor candidates, mediating cell
entry of hepatitis C virus (HCV) on the basis of their physical association with virions or with …
entry of hepatitis C virus (HCV) on the basis of their physical association with virions or with …
[HTML][HTML] Small molecule inhibition of hepatitis C virus E2 binding to CD81
SE VanCompernolle, AV Wiznycia, JR Rush… - Virology, 2003 - Elsevier
The hepatitis C virus (HCV) is a causal agent of chronic liver infection, cirrhosis, and
hepatocellular carcinoma infecting more than 170 million people. CD81 is a receptor for …
hepatocellular carcinoma infecting more than 170 million people. CD81 is a receptor for …
Crystallization and preliminary crystallographic studies on the large extracellular domain of human CD81, a tetraspanin receptor for hepatitis C virus
K Kitadokoro, G Galli, R Petracca, F Falugi… - … Section D: Biological …, 2001 - journals.iucr.org
The large extracellular domain of CD81, a member of the tetraspanin family and a receptor
protein for hepatitis C virus envelope E2 glycoprotein, has been expressed, purified and …
protein for hepatitis C virus envelope E2 glycoprotein, has been expressed, purified and …
Identification of conserved residues in the E2 envelope glycoprotein of the hepatitis C virus that are critical for CD81 binding
Hepatitis C virus (HCV) cell entry involves interaction between the viral envelope
glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 …
glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 …