[PDF][PDF] Hepatitis C virus receptor expression in normal and diseased liver tissue
GM Reynolds, HJ Harris, A Jennings, K Hu… - …, 2008 - Wiley Online Library
The principal site of hepatitis C virus (HCV) replication is the liver. HCV pseudoparticles
infect human liver derived cell lines and this suggests that liver‐specific receptors contribute …
infect human liver derived cell lines and this suggests that liver‐specific receptors contribute …
Mutations within the CD81-Binding Sites and Hypervariable Region 2 of the Envelope 2 Protein: Correlation with Treatment Response in Hepatitis C Virus–Infected …
WP Hofmann, C Sarrazin… - The Journal of …, 2003 - academic.oup.com
The hepatitis C virus (HCV) envelope 2 (E2) protein interacts with the cellular receptor CD81
in vitro. Within E2, 2 CD81-binding sites were described. E2-CD81 interaction has been …
in vitro. Within E2, 2 CD81-binding sites were described. E2-CD81 interaction has been …
Hepatitis C virus infection propagates through interactions between Syndecan‐1 and CD81 and impacts the hepatocyte glycocalyx
B Grigorov, E Reungoat, A Gentil dit Maurin… - Cellular …, 2017 - Wiley Online Library
The hepatitis C virus (HCV) infects hepatocytes after binding to heparan sulfate
proteoglycans, in particular Syndecan‐1, followed by recognition of the tetraspanin CD81 …
proteoglycans, in particular Syndecan‐1, followed by recognition of the tetraspanin CD81 …
Functional analysis of hepatitis C virus E2 glycoproteins and virus-like particles reveals structural dissimilarities between different forms of E2
A Owsianka, RF Clayton… - Journal of General …, 2001 - microbiologyresearch.org
Structure–function analysis of the hepatitis C virus (HCV) envelope glycoproteins, E1 and
E2, has been difficult due to the unavailability of HCV virions. Truncated soluble forms of E2 …
E2, has been difficult due to the unavailability of HCV virions. Truncated soluble forms of E2 …
Hepatitis C virus utilizes VLDLR as a novel entry pathway
S Ujino, H Nishitsuji, T Hishiki… - Proceedings of the …, 2016 - National Acad Sciences
Various host factors are involved in the cellular entry of hepatitis C virus (HCV). In addition to
the factors previously reported, we discovered that the very-low-density lipoprotein receptor …
the factors previously reported, we discovered that the very-low-density lipoprotein receptor …
Internalization and molecular interactions of human CD21 receptor
J Tessier, A Cuvillier, F Glaudet, AA Khamlichi - Molecular immunology, 2007 - Elsevier
The human CD21 is a receptor for cleavage fragments of the third complement component
and for Epstein-Barr virus. Previous mutational studies showed that the cytoplasmic domain …
and for Epstein-Barr virus. Previous mutational studies showed that the cytoplasmic domain …
Syndecan-1 serves as the major receptor for attachment of hepatitis C virus to the surfaces of hepatocytes
Q Shi, J Jiang, G Luo - Journal of virology, 2013 - Am Soc Microbiol
Our recent studies demonstrated that apolipoprotein E mediates cell attachment of hepatitis
C virus (HCV) through interactions with the cell surface heparan sulfate (HS). HS is known to …
C virus (HCV) through interactions with the cell surface heparan sulfate (HS). HS is known to …
T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck
Binding of the hepatitis C virus (HCV) envelope protein E2 to CD81 provides a costimulatory
signal for human T cells. This phenomenon may play a role in liver damage and …
signal for human T cells. This phenomenon may play a role in liver damage and …
Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: putative CD81 binding region 1 is not involved in CD81 binding
KB Rothwangl, B Manicassamy, SL Uprichard, L Rong - Virology journal, 2008 - Springer
Abstract Background Hepatitis C virus (HCV) encodes two transmembrane glycoproteins E1
and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been …
and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been …
Expression of CD81, SR‐BI and LDLR in lymphocytes and monocytes from patients with classic and occult hepatitis C virus infection
MC Roque‐Cuéllar, B Sánchez… - Journal of medical …, 2012 - Wiley Online Library
CD81, the scavenger receptor‐BI (SR‐BI) and the low‐density lipoprotein receptor (LDLR)
are involved in peripheral blood mononuclear cells (PBMCs) hepatitis C virus (HCV) entry …
are involved in peripheral blood mononuclear cells (PBMCs) hepatitis C virus (HCV) entry …