Cracking the BAFF code
F Mackay, P Schneider - Nature reviews immunology, 2009 - nature.com
The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …
The role of BAFF in immune function and implications for autoimmunity
SL Kalled - Immunological reviews, 2005 - Wiley Online Library
BAFF [B‐cell activating factor belonging to the tumor necrosis factor (TNF) family] is a ligand
that is required for peripheral B‐cell survival and homeostasis. In addition to mediating B …
that is required for peripheral B‐cell survival and homeostasis. In addition to mediating B …
BAFF: a local and systemic target in autoimmune diseases
I Moisini, A Davidson - Clinical & Experimental Immunology, 2009 - academic.oup.com
BAFF (B lymphocyte activating factor of the tumour necrosis factor family) is a vital
homeostatic cytokine for B cells that helps regulate both innate and adaptive immune …
homeostatic cytokine for B cells that helps regulate both innate and adaptive immune …
The BAFF/APRIL system: life beyond B lymphocytes
B cell activating factor belonging to the TNF family (BAFF) and a proliferation-inducing
ligand (APRIL) are two members of the TNF ligand superfamily. Studies of BAFF, APRIL and …
ligand (APRIL) are two members of the TNF ligand superfamily. Studies of BAFF, APRIL and …
Targeting BAFF in autoimmunity
A Davidson - Current opinion in immunology, 2010 - Elsevier
BAFF and APRIL are TNF-like cytokines that support survival and differentiation of B cells.
The early appreciation that overexpression of BAFF leads to B cell expansion and a lupus …
The early appreciation that overexpression of BAFF leads to B cell expansion and a lupus …
BAFF and the regulation of B cell survival
P Schneider, J Tschopp - Immunology letters, 2003 - Elsevier
The TNF family member BAFF is a fundamental survival factor for B cells. BAFF binds to
three receptors, only one of which, BAFF-R, does not cross-react with the BAFF-related …
three receptors, only one of which, BAFF-R, does not cross-react with the BAFF-related …
BAFF AND APRIL: a tutorial on B cell survival
F Mackay, P Schneider, P Rennert… - Annual review of …, 2003 - annualreviews.org
BAFF, a member of the TNF family, is a fundamental survival factor for transitional and
mature B cells. BAFF overexpression leads to an expanded B cell compartment and …
mature B cells. BAFF overexpression leads to an expanded B cell compartment and …
B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling
B-cell activation factor from the tumor necrosis factor family (BAFF) is a key survival factor
during B-cell maturation—a delicate immune checkpoint for B cells. Excessive BAFF …
during B-cell maturation—a delicate immune checkpoint for B cells. Excessive BAFF …
BAFF, APRIL and human B cell disorders
B cells require signals from multiple sources for their development from precursor cells, and
differentiation into effector cells. BAFF has been identified as a critical regulator of B cell …
differentiation into effector cells. BAFF has been identified as a critical regulator of B cell …
The biochemistry and biology of BAFF, APRIL and their receptors
SL Kalled, C Ambrose, YM Hsu - B Cell Trophic Factors and B Cell …, 2005 - karger.com
The tumor necrosis factor (TNF) family of related receptors and ligands contains a rich
collection of molecules that are important players in a broad spectrum of biological systems …
collection of molecules that are important players in a broad spectrum of biological systems …