Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive
decline of memory and cognitive function. The disease is characterized by the presence of …

Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by beta-amyloid
plaques (Aβ), neurofibrillary tangles (NFT), and neuroinflammation. Data have demonstrated …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Recent
evidence suggests that gamma-aminobutyric acid B (GABA B) receptor-mediated inhibition …

Alzheimer's disease (AD) is a leading cause of dementia, with no effective treatment
currently available. However, targeting the aging mechanism may improve outcomes and γ …

Conclusions: Our findings demonstrated that the GABAergic system suffers significant
remodeling in the brains of AD patients, yet it is to be determined if this is as a consequence …

Amyloid precursor protein (APP) modulates glutamate release via cytoplasmic and
intravesicular interactions with the synaptic vesicle release machinery. The intravesicular …

Background Alzheimer's disease (AD) is associated with gradual memory loss and anxiety
which affects~ 75% of AD patients. This study investigated whether AD‐associated anxiety …

Functioning at the interface between the nervous and immune systems, in the amyloid-
depositing brain, astrocytes become hypertrophic and accumulate around senile plaques …

GABA (gamma-aminobutyric acid) receptor modulators have been investigated as a
potential treatment strategy in Alzheimer's disease (AD). In the present study, we found that …

Aims GABAergic modulation involved in cognitive processing appears to be substantially
changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to …