The opportunistic Gram-negative bacterium Acinetobacter baumannii (AB) is a leading
cause of life-threatening nosocomial pneumonia. Outbreaks of multidrug resistant (MDR)-AB …

Acinetobacter baumannii is an emerging nosocomial, opportunistic pathogen with growing
clinical significance globally. A. baumannii has an exceptional ability to rapidly develop drug …

Abstract Acinetobacter baumannii (A. baumannii), one of the major pathogens that causes
severe nosocomial infections, is characterised by a high prevalence of drug resistance. It …

Acinetobacter baumannii is a multi‐drug resistant, Gram‐negative bacteria and infection
with this organism is one of the major causes of mortality in intensive care units …

Acinetobacter baumannii (A. baumannii) is a Gram-negative bacterium, which acts as an
opportunistic pathogen and causes hospital-acquired pneumonia and bacteremia by …

Inflammasomes are innate immune sensors that regulate caspase-1 mediated inflammation
in response to environmental, host-and pathogen-derived factors. The NLRP3 …

Background The NOD-like receptor (NLR) family pyrin domain-containing 3 (NLRP3)
inflammasomes are intracellular protein complexes that orchestrate immune responses …

Assembly of the inflammasome has recently been identified to be a critical event in the
initiation of inflammation. However, its role in bacterial killing remains unclear. Our study …

Streptococcus pneumoniae is the most frequently isolated causative pathogen of community-
acquired pneumonia, a leading cause of mortality worldwide. Inflammasomes are …

Bacterial flagellin is critical to mediate NLRC4 inflammasome-dependent caspase-1
activation. However, Shigella flexneri, a nonflagellated bacterium, and a flagellin (fliC) …