Assessment, origin, and implementation of breath volatile cancer markers

H Haick, YY Broza, P Mochalski, V Ruzsanyi… - Chemical Society …, 2014 - pubs.rsc.org
A new non-invasive and potentially inexpensive frontier in the diagnosis of cancer relies on
the detection of volatile organic compounds (VOCs) in exhaled breath samples. Breath can …

Review of recent developments in determining volatile organic compounds in exhaled breath as biomarkers for lung cancer diagnosis

J Zhou, ZA Huang, U Kumar, DDY Chen - Analytica chimica acta, 2017 - Elsevier
Lung cancer is the most common cause of cancer deaths, its global incidence is rising, and
continuing rises are predicted. The potential to diagnose lung cancers based on the …

Current challenges in volatile organic compounds analysis as potential biomarkers of cancer

K Schmidt, I Podmore - Journal of biomarkers, 2015 - Wiley Online Library
An early diagnosis and appropriate treatment are crucial in reducing mortality among people
suffering from cancer. There is a lack of characteristic early clinical symptoms in most forms …

Assessment of the exhalation kinetics of volatile cancer biomarkers based on their physicochemical properties

A Amann, P Mochalski, V Ruzsanyi… - Journal of breath …, 2014 - iopscience.iop.org
The current review provides an assessment of the exhalation kinetics of volatile organic
compounds (VOCs) that have been linked with cancer. Towards this end, we evaluate …

Detection of lung cancer: concomitant volatile organic compounds and metabolomic profiling of six cancer cell lines of different histological origins

Z Jia, H Zhang, CN Ong, A Patra, Y Lu, CT Lim… - ACS …, 2018 - ACS Publications
In recent years, there has been an extensive search for a non-invasive screening technique
for early detection of lung cancer. Volatile organic compound (VOC) analysis in exhaled …

Volatile organic compounds in human matrices as lung cancer biomarkers: A systematic review

E Janssens, JP van Meerbeeck, K Lamote - Critical Reviews in Oncology …, 2020 - Elsevier
Volatile organic compounds (VOCs) have shown potential as non-invasive breath
biomarkers for lung cancer, but their unclear biological origin currently limits clinical …

Critical review of volatile organic compound analysis in breath and in vitro cell culture for detection of lung cancer

Z Jia, A Patra, VK Kutty, T Venkatesan - Metabolites, 2019 - mdpi.com
Breath analysis is a promising technique for lung cancer screening. Despite the rapid
development of breathomics in the last four decades, no consistent, robust, and validated …

Breath based volatile organic compounds in the detection of breast, lung, and colorectal cancers: A systematic review

I Oakley-Girvan, SW Davis - Cancer Biomarkers, 2018 - content.iospress.com
BACKGROUND: Detecting volatile organic compounds (VOCs) could provide a rapid,
noninvasive, and inexpensive screening tool for detecting cancer. OBJECTIVE: In this …

Comparative analyses of volatile organic compounds (VOCs) from patients, tumors and transformed cell lines for the validation of lung cancer-derived breath markers

W Filipiak, A Filipiak, A Sponring… - Journal of breath …, 2014 - iopscience.iop.org
Breath analysis for the purpose of non-invasive diagnosis of lung cancer has yielded
numerous candidate compounds with still questionable clinical relevance. To arrive at …

Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD

IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …