Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

Oxygen free radicals in excessively high amounts are all very reactive chemically and can
impose a detrimental influence on living organisms by provoking “oxidative stress” that can …

Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

Virtually all inflammatory mediators investigated to date seem to be dysregulated in the
inflamed intestinal mucosa of patients with inflammatory bowel disease. However, which of …

Oxidative stress is defined by an imbalance between increased levels of reactive oxygen
species (ROS) and a low activity of antioxidant mechanisms. An increased oxidative stress …

Over the past several years, nutritional antioxidants have attracted considerable interest in
the popular press as potential treatment for a wide variety of disease states, including …

The gastrointestinal epithelium transports solutes and water between lumen and blood and
at the same time forms a barrier between these compartments. This highly selective and …

Crohn's disease and ulcerative colitis, known together as inflammatory bowel diseases
(IBDs), and celiac disease are the most common disorders affecting not only adults but also …

Oxidative stress in this section will refer to the availability of free radicals to react with target
tissues because of inadequate antioxidant capacity or bioavailability. One major target for …

Oxidative stress is thought to play a key role in the development of intestinal damage in
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …