Studies in which serotonergic drugs were administered either systemically or directly into
central sites have implicated 5-HT in the inhibitory control of feeding in mammals. In animal …

Serotonin has been implicated in the control of satiety for almost four decades. Historically,
the insight that the appetite suppressant effect of fenfluramine is linked to serotonin has …

Serotonin (5-HT) receptor agonists with high affinity for the different subtypes (ie 5-HT1A–1F,
5-HT2A–2C) of the 5-HT1-and 5-HT2 receptor families have been shown to affect ingestive …

Evidence to date suggests an inhibitory role for serotonin (5-HT) in the regulation of feeding
behavior. In the present study, hypothalamic 5-HT was investigated for its anorexic potency …

Abstract Serotonin (5-HT) is believed to have an inhibitory influence over feeding behavior.
The present experiments were designed to investigate the effects of hypothalamic 5-HT on …

Previous studies have demonstrated that injection of serotonin (5-HT) into the
paraventricular nucleus (PVN), specifically at the onset of the active feeding cycle, causes a …

Serotonin (5-HT) has been implicated in the control of eating behavior and body weight.
Stimulants of this monoamine reduce food intake and weight gain and increase energy …

Feeding or food withdrawal can affect the supply of tryptophan to the brain and hence (in
some circumstances) 5-HT synthesis therein. Also fenfluramine which releases 5-HT to …

The effects of nine central 5-HT antagonists on food intake in free feeding male rats were
examined. The 5-HT 2 antagonists ritanserin and ketanserin and the selective 5-HT 3 …

Recent pharmacological studies have more precisely characterised the nature of the
inhibitory effect of brain serotonin (5-hydroxytryptamine) on feeding behaviour. Thus, the …