Genome-wide association study identifies new susceptible loci of IgA nephropathy in Koreans

KH Jeong, JS Kim, YH Lee, YG Kim, JY Moon… - BMC Medical …, 2019 - Springer
Abstract Background Immunoglobulin A nephropathy (IgAN) is the most common primary
glomerulonephritis worldwide. Recent evidence suggests that genetic factors are related to …

Replication of genome‐wide association study identified seven susceptibility genes, affirming the effect of rs2856717 on renal function and poor outcome of IgA …

W Wang, G Li, D Hong, Y Zou, D Fei, L Wang - Nephrology, 2017 - Wiley Online Library
Aim Meta‐analysis of data from a genome‐wide association study (GWAS) identified seven
single nucleotide polymorphisms (SNPs) as strong predictors of IgA nephropathy (IgAN). To …

An Update on the Genetics of IgA Nephropathy

LL Xu, XJ Zhou, H Zhang - Journal of Clinical Medicine, 2023 - mdpi.com
Immunoglobulin A (IgA) nephropathy (IgAN), the most common form of glomerulonephritis, is
one of the leading causes of end-stage kidney disease (ESKD). It is widely believed that …

Genome-wide association study of IgA nephropathy using 23 465 microsatellite markers in a Japanese population

S Saka, N Hirawa, A Oka, K Yatsu, T Hirukawa… - Journal of human …, 2015 - nature.com
Immunoglobulin A nephropathy (IgAN) is the most common form of primary
glomerulonephritis in many parts of the world. Although previous genome-wide association …

Trans-ethnic analysis of susceptibility variants in IgA nephropathy

YQ Kang, YM Zhang, P Hou, SF Shi, LJ Liu… - Beijing da xue xue …, 2019 - europepmc.org
Objective To compare the genetic architecture of susceptibility variants of IgA nephropathy
(IgAN) in Chinese and Europeans. Methods We selected the independent genome-wide …

Identification of new susceptibility loci for IgA nephropathy in Han Chinese

M Li, JN Foo, JQ Wang, HQ Low, XQ Tang… - Nature …, 2015 - nature.com
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis. Previously
identified genome-wide association study (GWAS) loci explain only a fraction of disease risk …

Genome-wide meta-analysis identifies three novel susceptibility loci and reveals ethnic heterogeneity of genetic susceptibility for IgA nephropathy

M Li, L Wang, DC Shi, JN Foo, Z Zhong… - Journal of the …, 2020 - journals.lww.com
Background Eighteen known susceptibility loci for IgAN account for only a small proportion
of IgAN risk. Methods Genome-wide meta-analysis was performed in 2628 patients and …

Genetic study of immunoglobulin A nephropathy: From research to clinical application

M Li, X Yu - Nephrology, 2018 - Wiley Online Library
Immunoglobulin A nephropathy (IgAN) is one of the most common primary
glomerulonephritis throughout the world and a major cause of end‐stage renal disease …

Cumulative effects of variants identified by genome-wide association studies in IgA nephropathy

XJ Zhou, YY Qi, P Hou, JC Lv, SF Shi, LJ Liu, N Zhao… - Scientific Reports, 2014 - nature.com
The effect of genetic markers associated with IgA nephropathy on risk of disease in sub-
phenotype and progression is uncertain. Data from 2096 Chinese patients were used to …

Genetic determinants of IgA nephropathy: eastern perspective

M Li, XQ Yu - Seminars in Nephrology, 2018 - Elsevier
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritides
throughout the world and a major cause of end-stage renal disease among the East Asian …