Importance of the field: Current antibiotics have classically been developed to treat
infections involving planktonic bacterial populations in acute infection settings and are …

Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …

Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …

Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

Introduction: As a result of progress in medical care, a huge number of medical devices are
used in the treatment of human diseases. In turn, biofilm-related infection has become a …

Since the 1960's much research has focused on biofilms, ie microbial-derived populations
irreversibly attached to a surface and embedded in a self-produced polymeric matrix. In this …

Biofilms, defined as a surface attached community of bacteria embedded in a matrix of
extracellular polymeric substances, are a significant global health problem, causing …

Highlights•Biofilm infections are heterogenous, persistent and recalcitrant.•The rise of
antibiotic resistance necessitates new therapeutic strategies to eradicate biofilms.•The …

Biofilms are responsible for more than 80% of all chronic infections and represent an
enormous medical challenge. In order to meet this challenge, translation research on anti …

Microbial biofilms, which are elaborate and highly resistant microbial aggregates formed on
surfaces or medical devices, cause two-thirds of infections and constitute a serious threat to …