[HTML][HTML] Peptide-based materials for cancer immunotherapy

L Zhang, Y Huang, AR Lindstrom, TY Lin, KS Lam… - Theranostics, 2019 - ncbi.nlm.nih.gov
Peptide-based materials hold great promise as immunotherapeutic agents for the treatment
of many malignant cancers. Extensive studies have focused on the development of peptide …

Peptide-based anticancer vaccines: recent advances and future perspectives

S Mocellin, P Pilati, D Nitti - Current medicinal chemistry, 2009 - ingentaconnect.com
Anticancer active immunotherapy embodies the ideal antitumor therapy, as it theoretically
combines target specificity with long-term disease control. Peptide-based cancer vaccines …

Sequentially responsive therapeutic peptide assembling nanoparticles for dual-targeted cancer immunotherapy

K Cheng, Y Ding, Y Zhao, S Ye, X Zhao, Y Zhang… - Nano …, 2018 - ACS Publications
Combination therapeutic regimen is becoming a primary direction for current cancer
immunotherapy to broad the antitumor response. Functional nanomaterials offer great …

Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability

KD Moynihan, RL Holden, NK Mehta, C Wang… - Cancer immunology …, 2018 - AACR
Antitumor T-cell responses have the potential to be curative in cancer patients, but the
induction of potent T-cell immunity through vaccination remains a largely unmet goal of …

Insights on peptide vaccines in cancer immunotherapy

KY Tsang, C Jochems, J Schlom - Developments in T cell based cancer …, 2015 - Springer
Human tumor-associated antigens are generally weakly immunogenic and therefore able to
escape detection by the immune system. Numerous studies have shown, however, that …

Tumor growth inhibition by mSTEAP peptide nanovaccine inducing augmented CD8+ T cell immune responses

Q Chen, Y Bao, D Burner, S Kaushal, Y Zhang… - Drug delivery and …, 2019 - Springer
Abstract Poly (lactic-co-glycolic) acid (PLGA) has been successfully used in drug delivery
and biomaterial applications, but very little attention has been directed towards the potential …

Fully synthetic Mincle-dependent self-adjuvanting cancer vaccines elicit robust humoral and T cell-dependent immune responses and protect mice from tumor …

X Luo, Q Lian, W Li, L Chen, R Zhang, D Yang… - Chemical …, 2021 - pubs.rsc.org
A new strategy based on a macrophage-inducible C-type lectin (Mincle) agonist was
established to construct synthetic cancer vaccines. Using sialyl-Tn (STn) as a model antigen …

Clickable amino acid derivative tuned self-assembly of antigen and adjuvant for cancer immunotherapy

X He, L Yang, H Su, S Lin, D Qi, H Chen, Y Qu… - Journal of Controlled …, 2021 - Elsevier
Amino acid-tuned self-assembly has become an attractive strategy for constructing various
functional materials. Here, a series of dibenzocyclooctyne (DIBO) functionalized amphiphilic …

[HTML][HTML] Current approaches in development of immunotherapeutic vaccines for breast cancer

A Allahverdiyev, G Tari, M Bagirova… - Journal of breast …, 2018 - synapse.koreamed.org
Cancer is the leading cause of death worldwide. In developed as well as developing
countries, breast cancer is the most common cancer found among women. Currently …

Targeting cross-presentation as a route to improve the efficiency of peptide-based cancer vaccines

B Wylie, F Ong, H Belhoul-Fakir, K Priebatsch… - Cancers, 2021 - mdpi.com
Simple Summary Cancer vaccination is a potential anti-cancer therapy which may improve
clinical outcomes, particularly in combination with current immunotherapies, but to date has …