The epithelial–mesenchymal transition (EMT) plays a crucial role in pancreatic ductal
adenocarcinoma (PDAC) development and progression. TWIST activated by intra-tumoral …

Cancer-associated fibroblasts (CAFs) play critical roles in tumor progression. However, the
role and mechanism underlying CAFs in esophageal cancer (EC) remain unclear. In this …

Purpose: Hepatocellular carcinoma (HCC) is a rapidly growing tumor associated with a high
propensity for vascular invasion and metastasis. Epithelial-mesenchymal transition (EMT) is …

Background Twist, a transcription factor of the basic helix-loop-helix class, is reported to
regulate cancer metastasis. It is known to induce epithelial-mesenchymal transition (EMT). In …

Hypoxia promotes tumor invasion and metastasis via multiple mechanisms, including
epithelial-mesenchymal transition (EMT). Twist, an EMT regulator, has been disclosed to …

Objectives: Expression of transcription factors that mediate epithelial-mesenchymal
transition (EMT), such as Twist and Slug, is correlated with poor prognosis in many tumor …

Angiogenesis is a critical step in the growth and dissemination of malignant diseases,
including pancreatic cancer. Twist has been shown to stimulate angiogenesis in the tumor …

E‐cadherin loss is a key biological mechanism in tumour invasion. As a main regulator of
epithelial‐mesenchymal transition (EMT) mechanism‐mediated invasion and metastasis …

Overexpression of Twist, a highly conserved basic helix-loop-helix transcription factor, is
associated with epithelial-mesenchymal transition (EMT) and predicts poor prognosis in …

Epithelial-to-mesenchymal transition (EMT) facilitates tumor metastasis. Twist is a basic helix-
loop-helix protein that modulates many target genes through E-box-responsive elements …