Constructing multifunctional Cu single-atom nanozyme for synergistic nanocatalytic therapy-mediated multidrug-resistant bacteria infected wound healing

X Qiu, L Zhuang, J Yuan, H Wang, X Dong, S He… - Journal of Colloid and …, 2023 - Elsevier
Developing an effective strategy to combat multi-drug-resistant (MDR) bacteria and promote
wound healing without overuse of antibiotics remains an important and challenging goal …

CuO2-assisting-Zn single atom hybrid nanozymes for biofilm-infected wound healing

J Song, H Chen, Y Lv, W Yang, F Zhang, T Wang… - Chemical Engineering …, 2023 - Elsevier
Abstract Single-atom catalysts (SACs), characterized by atomically dispersed single metal
atoms, provide superior antibacterial properties over common nanozyme materials due to …

Multifunctional Pd single-atom nanozyme for enhanced cascade chemodynamic therapy of chronic wounds

X Xu, J Zhang, X Wang, H Fang, S Shi… - ACS Applied Nano …, 2024 - ACS Publications
Nanozymes are considered promising therapeutic agents for infected chronic wounds due to
their enzyme-like activity-mediated chemodynamic therapy (CDT). However, they still suffer …

Alternative copper-based single-atom nanozyme with superior multienzyme activities and nir-ii responsiveness to fight against deep tissue infections

J Bai, Y Feng, W Li, Z Cheng, JM Rosenholm, H Yang… - Research, 2023 - spj.science.org
Nanozymes are considered to represent a new era of antibacterial agents, while their
antibacterial efficiency is limited by the increasing tissue depth of infection. To address this …

Aptamer and DNAzyme-functionalized Cu-MOF hybrid nanozymes for the monitoring and management of bacteria-infected wounds

F Mo, S Zhong, T You, J Lu, D Sun - ACS Applied Materials & …, 2023 - ACS Publications
Metal–organic frameworks (MOFs) with peroxidase (POD)-like activity have great potential
for combating drug-resistant bacterial infections. However, the use of POD-like activities is …

Bimetallic CuCo2S4 Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

D Li, Q Guo, L Ding, W Zhang, L Cheng… - …, 2020 - Wiley Online Library
Peroxidase‐mimicking nanozymes that can generate toxic hydroxyl radicals (. OH) hold
great promise as antibacterial alternatives. However, most of them display optimal …

Ag-Activated Metal−Organic Framework with Peroxidase-like Activity Synergistic Ag+ Release for Safe Bacterial Eradication and Wound Healing

J Zhou, N Chen, J Liao, G Tian, L Mei, G Yang, Q Wang… - Nanomaterials, 2022 - mdpi.com
Silver nanoparticles (Ag NPs), a commonly used antibacterial nanomaterial, exhibit broad-
spectrum antibacterial activity to combat drug-resistant bacteria. However, the Ag NPs often …

Bioinspired copper single‐atom nanozyme as a superoxide dismutase‐like antioxidant for sepsis treatment

J Yang, R Zhang, H Zhao, H Qi, J Li, JF Li, X Zhou… - …, 2022 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome with high morbidity and mortality
mediated by infection‐caused oxidative stress. Early antioxidant intervention by removing …

Cu-GA-coordination polymer nanozymes with triple enzymatic activity for wound disinfection and accelerated wound healing

H Tian, J Yan, W Zhang, H Li, S Jiang, H Qian, X Chen… - Acta Biomaterialia, 2023 - Elsevier
During the past few years, bacterial infection and oxidative stress have become important
issues for wound healing. However, the emergence of numerous drug-resistant superbugs …

Quaternized chitosan coated copper sulfide nanozyme with peroxidase-like activity for synergistic antibacteria and promoting infected wound healing

B Luo, J Cai, Y Xiong, X Ding, X Li, S Li, C Xu… - International Journal of …, 2023 - Elsevier
Bacterial infection can hinder the infected wound healing process. Because of the growing
drug-resistance bacteria, there is an urgent desire to develop alternative antibacterial …