Macrophages are pivotal in the initiation and development of atherosclerotic cardiovascular
diseases. Recent studies have reinforced the importance of mitochondria in metabolic and …

Atherosclerotic cardiovascular disease is a major cause of morbidity and mortality due to
chronic arterial injury caused by hyperlipidemia, hypertension, inflammation and oxidative …

Inflammation is a key process in metazoan organisms due to its relevance for innate defense
against infections and tissue damage. However, inflammation is also implicated in …

Atherosclerosis is a complex disorder that involves several mechanisms of pathogenesis
tightly related to each other: lipid accumulation, inflammation and structural changes in the …

Mitochondria are highly dynamic organelles beyond powerhouses of a cell. These
components also play important roles in cell homeostasis by regulating cell function and …

The eukaryote's mitochondrial network is perhaps the cell's most sophisticated and dynamic
responsive sensing system. Integrating metabolic, oxygen, or danger signals with inputs …

Traditionally, the mitochondria have been viewed as the cell's powerhouse, producing
energy in the form of ATP. As a byproduct of ATP formation, the mitochondrial electron …

Mitochondria are often regarded as the powerhouse of the cell by generating the ultimate
energy transfer molecule, ATP, which is required for a multitude of cellular processes …

The mitochondrion plays a crucial role in the immune system particularly in regulating the
responses of monocytes and macrophages to tissue injury, pathogens, and inflammation. In …

Atherosclerosis is a complex pathology that involves both metabolic dysfunction and chronic
inflammatory process. During the last decade, a considerable progress was achieved in …