Nitric oxide (NO) is a very labile molecule of ubiquitous significance in biological systems in
general. During the past two decades, NO has been recognized as one of the most versatile …

Nitric oxide (NO) was initially described as a physiological mediator of endothelial cell
relaxation, an important role in hypotension. NO is an intercellular messenger that has been …

Publisher Summary This chapter examines the multiple roles that nitric oxide (NO) may play
during the inflammatory response. The majority of data implicating a role for NO in …

The role of nitric oxide (NO) derived from constitutive (cNOS) and inducible (iNOS) nitric
oxide synthases and its relationship to oxygen-derived free radicals and prostaglandins was …

Nitric oxide (NO) is a colorless gas at room temperature and is one of the simplest molecules
known. For more than 300 years, it was considered mainly as an environmental pollutant …

Nitric oxide (NO) is synthesised by many cell types involved in immunity and inflammation.
The principal enzyme involved is the inducible type-2 isoform of nitric oxide synthase (NOS …

Nitric oxide (NO) has complex and diverse functions in physiological and pathophysiological
phenomena. The mechanisms of many events induced by NO are now well defined, so that …

Publisher Summary Local and systemic inflammation is characterized by the overproduction
of nitric oxide (NO). In most instances, the source of this NO is the inducible isoform of NO …

Despite a number of discussions and controversies, it now well established that nitric oxide
(NO) plays an important regulatory role in the initiation and development of various …

The role of nitric oxide (NO) in inflammation represents one of the most studied yet
controversial subjects in physiology. A number of reports have demonstrated that NO …