Objective: To explore the theraputic effects and potential mechanisms of hydrogen-rich
water (HRW) against oxalate-induced kidney injury. Methods: The mouse model of Calcium …

Objective: The study aimed to evaluate the preventive effects of hydroxycitric acid (HCA) for
stone formation in the glyoxylate-induced mouse model. Materials and Methods: Male …

Background. Kidney stone disease induces chronic renal insufficiency by crystal‐induced
renal tubular epithelial cell injury. It has been reported that the prevalence of kidney stone …

Background. Nephrolithiasis is a common disease that seriously affects the health and life
quality of patients. Despite the reported effect of hyperoside (Hyp) against nephrolithiasis …

Background Congenital obstructive nephropathy (CKD) is commonly implicated in the
pathophysiology of chronic kidney disease occurring in the pediatric and adolescent age …

Purpose: Acute kidney injury (AKI) is a prominent risk factor for the development of chronic
kidney disease (CKD). To date, the related mechanism and effective therapy have not been …

Ursolic acid (UA) has been proved to have antioxidant and anti-inflammatory effects.
However, it is not clear whether it has a protective impact on kidney damage induced by …

Enhanced sodium excretion is associated with intrarenal oxidative stress. The present study
evaluated whether oxidative stress caused by high sodium (HS) may be involved in calcium …

The aim of this study is to evaluate the protective effect and underlying mechanism of
hydrogen gas (H 2) to glyoxylate induced renal calcium oxalate (CaOx) crystal deposition in …

Background High prevalence and reoccurrence rate of nephrolithiasis bring about serious
socioeconomic and healthcare burden, necessitating the need of effective therapeutic …