Determination of Cytisine and N-Methylcytisine from Selected Plant Extracts by High-Performance Liquid Chromatography and Comparison of Their Cytotoxic Activity

A Petruczynik, K Wróblewski, J Misiurek, T Plech… - Toxins, 2020 - mdpi.com
Quinolizidine alkaloids exhibit various forms of biological activity. A lot of them were found in
the Leguminosae family, including Laburnum and Genista. The aim of the study was the …

Comparison of various chromatographic systems for analysis of cytisine in human serum, saliva and pharmaceutical formulation by HPLC with diode array …

K Wróblewski, A Petruczynik, T Tuzimski, D Przygodzka… - Molecules, 2019 - mdpi.com
Background: Identification and quantitative determination of cytisine, especially in biological
samples and pharmaceutical formulations, is still a difficult analytical task. Cytisine is an …

Determination of some isoquinoline alkaloids in extracts obtained from selected plants of the Ranunculaceae, Papaveraceae and Fumarioideae families by liquid …

J Misiurek, T Plech, B Kaproń, A Makuch-Kocka… - Molecules, 2023 - mdpi.com
Alkaloids are heterocyclic bases with widespread occurrence in nature. Plants are rich and
easily accessible sources of them. Most isoquinoline alkaloids have cytotoxic activity for …

Determination of selected isoquinoline alkaloids from Mahonia aquifolia; Meconopsis cambrica; Corydalis lutea; Dicentra spectabilis; Fumaria officinalis; Macleaya …

A Petruczynik, T Plech, T Tuzimski, J Misiurek… - Toxins, 2019 - mdpi.com
Alkaloids have protective functions for plants and can play an important role in living
organisms. Alkaloids may have a wide range of pharmacological activities. Many of them …

[PDF][PDF] Chemical composition and cytotoxic activity of Centaurea scoparea Sieb against four human cell lines

AM Beltagy - Journal of Pharmaceutical Sciences and Research, 2015 - researchgate.net
The aim of this work was to investigate the lipoidal matter composition of the petroleum ether
extract of Centaurea scoparea Sieb, to determine the total flavonoidal content of the …

[PDF][PDF] HPTLC densitomeric determination of justicidin B in Linum in vitro cultures

N Vasilev, P Nedialkov, I Ionkova… - Die Pharmazie-An …, 2004 - researchgate.net
The lignans comprise a class of natural products, which are derived from cinnamic acid
derivatives, and which are related biochemically to phenylalanine metabolism (Moss 2000) …

Isolation of alkaloids and anti-tumor activity of the crude methanolic extract of Algerian Cytisus purgans

G Benaiche, N Belattar, S Trifunović, N Vukovic… - 2015 - scidar.kg.ac.rs
In this study, two known quinolizidine alkaloids which are sparteine and lupanine were
isolated from the methanolic extract of the plant Cytisus purgans of Algerian flora by open …

Cytotoxic and Proapoptotic Activity of Sanguinarine, Berberine, and Extracts of Chelidonium majus L. and Berberis thunbergii DC. toward Hematopoietic Cancer Cell …

A Och, D Zalewski, Ł Komsta, P Kołodziej, J Kocki… - Toxins, 2019 - mdpi.com
Isoquinoline alkaloids belong to the toxic secondary metabolites occurring in plants of many
families. The high biological activity makes these compounds promising agents for use in …

Cytotoxic activity of Catharanthus roseus (Apocynaceae) crude extracts and pure compounds against human colorectal carcinoma cell line.

MJ Siddiqui, Z Ismail, AFA Aisha, AMS Abdul Majid - 2010 - cabidigitallibrary.org
Abstract Catharanthus roseus (Apocynaceae), in Malaysia known as Kemuning cina, well
known for being rich in alkaloids was investigated for its cytotoxic activity by using MTT …

Comparison of Anticancer Activity and HPLC-DAD Determination of Selected Isoquinoline Alkaloids from Thalictrum foetidum, Berberis sp. and Chelidonium majus …

A Petruczynik, T Tuzimski, T Plech, J Misiurek… - Molecules, 2019 - mdpi.com
Background: Plants are an important origin of natural substances that the raw material for
various pharmaceutical and therapeutic applications due to the presence of phytochemicals …