Carcinoembryonic antigen (CEA) presentation and specific T cell-priming by human dendritic cells transfected with CEA-mRNA

E Eppler, H Hörig, HL Kaufman, P Groscurth… - European Journal of …, 2002 - Elsevier
The feasibility of dendritic cells (DC) for cancer immunotherapy after transfection by
electroporation with mRNA encoding the human carcinoembryonic antigen (CEA) was …

Induction of carcinoembryonic antigen (cea)‐specific cytotoxic t‐lymphocyte responses In vitro using autologous dendritic cells loaded with cea peptide or cea rna in …

SK Nair, S Hull, D Coleman, E Gilboa… - … journal of cancer, 1999 - Wiley Online Library
The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies
on the generation of potent DC capable of presenting tumor antigens such as …

In vitro induction of carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses

HI Cho, HJ Kim, ST Oh, TG Kim - Vaccine, 2003 - Elsevier
Carcinoembryonic antigen (CEA), which is expressed in several cancer types, is a potential
target for specific immunotherapy. In this study, the feasibility of using dendrite cells (DCs) …

Protective anti-tumour immune responses by murine dendritic cells pulsed with recombinant Tat-carcinoembryonic antigen derived from Escherichia coli

MY Bae, NH Cho, SY Seong - Clinical & Experimental …, 2009 - academic.oup.com
Carcinoembryonic antigen (CEA) is over-expressed on various human cancer cells and has
been the target of immunotherapies using dendritic cells (DCs) pulsed with CEA-specific …

Dendritic cells pulsed with CEA peptide induce CEA-specific CTL with restricted TCR repertoire

SE Alters, JR Gadea, M Sorich… - Journal of …, 1998 - journals.lww.com
The human carcinoembryonic antigen (CEA), which is expressed in several cancer types is
a potential target for antigen-specific immunotherapy. In this study, we show that dendritic …

Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA

MA Morse, SK Nair, PJ Mosca, AC Hobeika… - Cancer …, 2003 - Taylor & Francis
Immunizations with dendritic cells (DC) transfected with RNA encoding tumor antigens
induce potent tumor antigen-specific immune responses in vitro and in murine models. We …

Immunotherapy of cancer: generation of CEA specific CTL using CEA peptide pulsed dendritic cells

SE Alters, JR Gadea, R Philip - Dendritic Cells in Fundamental and …, 1997 - Springer
Antigen specific cytotoxic T lymphocytes (CTL) are being studied for their potential
immunotherapeutic benefit in the treatment of cancer. Carcinoembryonic antigen (CEA) is an …

Successful cancer vaccine therapy for carcinoembryonic antigen (CEA)‐expressing colon cancer using genetically modified dendritic cells that express CEA and T …

T Ojima, M Iwahashi, M Nakamura… - … journal of cancer, 2007 - Wiley Online Library
This study was designed to determine whether the vaccination of genetically modified
dendritic cells (DCs) simultaneously expressing carcinoembryonic antigen (CEA) …

Carcinoembryonic antigen as a target to induce anti-tumor immune responses

P Sarobe, E Huarte, JJ Lasarte… - Current cancer drug …, 2004 - ingentaconnect.com
Identification of relevant targets for cancer therapy is a major goal in cancer research. In this
field, the identification of tumor antigens has opened the possibility of inducing specific anti …

[HTML][HTML] Vaccination of colorectal cancer patients with CEA-loaded dendritic cells: antigen-specific T cell responses in DTH skin tests

WJ Lesterhuis, IJM De Vries, DH Schuurhuis… - Annals of …, 2006 - Elsevier
Abstract Background Dendritic cells (DCs) are the professional antigen-presenting cells of
the immune system. As such they are currently used in clinical vaccination protocols in …