The modular organization of nervous systems is a widely documented principle of design for
both vertebrate and invertebrate brains of which the columnar organization of the neocortex …

With the discoveries by Mountcastle and Hubel and Wiesel 2, it was recognized that a
fundamental feature of the cortical architecture is its columnar organization-that is, the …

The mammalian neocortex has six main layers distinguished by neuronal morphology and
density. Like the other distinct regions of the adult cerebral cortex, the neocortex is divided …

The appearance of the neocortex, its expansion, and its differentiation in mammals,
represents one of the principal episodes in the evolution of the vertebrate brain. One of the …

The modular construction of brain tissue is not solely a feature of vertebrate nervous tissue,
but is characteristic of many invertebrate nervous systems as well. Modern vertebrate and …

The adult mammalian neocortex consists of numerous' areas' distinguished from one
another largely on the basis of distinctions in cytoarchitecture and connections. The …

The number of neuronal cell bodies has been counted in a narrow strip (30 micrometers)
through the depth of the neocortex in several different functional areas (motor, somatic …

During the last 20 years, the understanding of the cerebral cortex has been dominated by
the concept of columnar organization. The term cortical column was first used to designate …

Pondering the immense complexity of the nervous system, one is overwhelmed at once by
the sheer number of neurons in the higher animals (roughly 3 x 101 in man) 1; this means …

The primate cerebral cortex is a sheet composed of many distinct areas. Each of these areas
receives a large number of afferent inputs from other cortical areas (and elsewhere) and in …