Progressive skeletal muscle wasting in cancer cachexia involves a process of dysregulated
protein synthesis and breakdown. This catabolism may be the result of mal‐nutrition, and an …

Cancer results in perturbations in skeletal muscle protein metabolism leading to muscle
wasting. Although severe wasting is seen primarily in persons with advanced malignancies …

Cancer cachexia (CC) is a debilitating multifactorial syndrome, involving progressive
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …

Cancer cachexia—cancer-associated body weight and muscle loss—is a significant
predictor of mortality and morbidity in cancer patients across a variety of cancer types …

Background Low muscle in cancer is associated with an increase in treatment‐related
toxicities and is a predictor of cancer‐related and all‐cause mortality. The mechanisms of …

BACKGROUND Cancer–associated cachexia is a syndrome of progressive wasting of body
energy (adipose) and protein (skeletal muscle) reserves. Cachexia occurs in a majority of …

Cachexia is a syndrome characterized by involuntary weight loss and wasting of skeletal
muscle mass. It is associated with worse overall survival and quality of life. The cancer …

Cancer is frequently associated with anorexia, weight loss, negative nitrogen balance, and
skeletal-muscle wasting. Depletion of skeletal-muscle mass is critical to overall survival of …

Cancer-associated cachexia (cancer cachexia) is a major contributor to the modality and
mortality of a wide variety of solid tumors. It is estimated that cachexia inflicts approximately …

Cachexia, the unintentional loss of body weight, is prevalent in many cancer types, and the
associated skeletal muscle mass depletion increases patient morbidity and mortality. While …