The role of systemic inflammation in cancer‐associated muscle wasting and rationale for exercise as a therapeutic intervention
Progressive skeletal muscle wasting in cancer cachexia involves a process of dysregulated
protein synthesis and breakdown. This catabolism may be the result of mal‐nutrition, and an …
protein synthesis and breakdown. This catabolism may be the result of mal‐nutrition, and an …
The biological mechanisms of cancer-related skeletal muscle wasting: the role of progressive resistance exercise
S Al-Majid, H Waters - Biological research for nursing, 2008 - journals.sagepub.com
Cancer results in perturbations in skeletal muscle protein metabolism leading to muscle
wasting. Although severe wasting is seen primarily in persons with advanced malignancies …
wasting. Although severe wasting is seen primarily in persons with advanced malignancies …
Nutraceuticals and exercise against muscle wasting during cancer cachexia
Cancer cachexia (CC) is a debilitating multifactorial syndrome, involving progressive
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …
Muscle alterations in the development and progression of cancer-induced muscle atrophy: a review
ME Rosa-Caldwell, DK Fix… - Journal of applied …, 2020 - journals.physiology.org
Cancer cachexia—cancer-associated body weight and muscle loss—is a significant
predictor of mortality and morbidity in cancer patients across a variety of cancer types …
predictor of mortality and morbidity in cancer patients across a variety of cancer types …
Muscle wasting in cancer: opportunities and challenges for exercise in clinical cancer trials
Background Low muscle in cancer is associated with an increase in treatment‐related
toxicities and is a predictor of cancer‐related and all‐cause mortality. The mechanisms of …
toxicities and is a predictor of cancer‐related and all‐cause mortality. The mechanisms of …
Management of muscle wasting in cancer‐associated cachexia: Understanding gained from experimental studies
VE Baracos - … International Journal of the American Cancer …, 2001 - Wiley Online Library
BACKGROUND Cancer–associated cachexia is a syndrome of progressive wasting of body
energy (adipose) and protein (skeletal muscle) reserves. Cachexia occurs in a majority of …
energy (adipose) and protein (skeletal muscle) reserves. Cachexia occurs in a majority of …
Physical exercise at the crossroad between muscle wasting and the immune system: implications for lung cancer cachexia
F Cortiula, LEL Hendriks… - Journal of cachexia …, 2022 - Wiley Online Library
Cachexia is a syndrome characterized by involuntary weight loss and wasting of skeletal
muscle mass. It is associated with worse overall survival and quality of life. The cancer …
muscle mass. It is associated with worse overall survival and quality of life. The cancer …
Regulation of skeletal-muscle–protein turnover in cancer-associated cachexia
VE Baracos - Nutrition, 2000 - Elsevier
Cancer is frequently associated with anorexia, weight loss, negative nitrogen balance, and
skeletal-muscle wasting. Depletion of skeletal-muscle mass is critical to overall survival of …
skeletal-muscle wasting. Depletion of skeletal-muscle mass is critical to overall survival of …
Cancer takes a toll on skeletal muscle by releasing heat shock proteins—an emerging mechanism of cancer-induced cachexia
Cancer-associated cachexia (cancer cachexia) is a major contributor to the modality and
mortality of a wide variety of solid tumors. It is estimated that cachexia inflicts approximately …
mortality of a wide variety of solid tumors. It is estimated that cachexia inflicts approximately …
Understanding the role of exercise in cancer cachexia therapy
Cachexia, the unintentional loss of body weight, is prevalent in many cancer types, and the
associated skeletal muscle mass depletion increases patient morbidity and mortality. While …
associated skeletal muscle mass depletion increases patient morbidity and mortality. While …
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