Repurposing non-cancer Drugs in Oncology–How many drugs are out there?
P Pantziarka, V Sukhatme, L Meheus, V Sukhatme… - bioRxiv, 2017 - biorxiv.org
Background Drug repurposing can speed up access to new therapeutic options for cancer
patients. With more than 2000 drugs approved worldwide and 6 relevant targets per drug on …
patients. With more than 2000 drugs approved worldwide and 6 relevant targets per drug on …
Drug repurposing in oncology—patient and health systems opportunities
In most countries, healthcare service budgets are not likely to support the current explosion
in the cost of new oncology drugs. Repurposing the large arsenal of approved, non …
in the cost of new oncology drugs. Repurposing the large arsenal of approved, non …
Drug repurposing for cancer therapy, easier said than done
A Gonzalez-Fierro, A Dueñas-González - Seminars in cancer biology, 2021 - Elsevier
Drug repurposing for cancer therapy is currently a hot topic of research. Theoretically, in
contrast to the known hurdles of developing new molecular entities, the approach of …
contrast to the known hurdles of developing new molecular entities, the approach of …
Drug repurposing—an emerging strategy in cancer therapeutics
KS Turabi, A Deshmukh, S Paul, D Swami… - Naunyn-Schmiedeberg's …, 2022 - Springer
Cancer is a complex disease affecting millions of people around the world. Despite
advances in surgical and radiation therapy, chemotherapy continues to be an important …
advances in surgical and radiation therapy, chemotherapy continues to be an important …
Repurposing drugs in oncology: next steps
C Verbaanderd, L Meheus, I Huys, P Pantziarka - Trends in cancer, 2017 - cell.com
The repurposing of existing non-cancer drugs is a potential source of new treatment options
for cancer patients with high unmet medical needs. While scientific research is progressing …
for cancer patients with high unmet medical needs. While scientific research is progressing …
Overcoming cancer therapeutic bottleneck by drug repurposing
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …
the development of the alternative strategy of drug repurposing, the development of old …
Can any drug be repurposed for cancer treatment? A systematic assessment of the scientific literature
N Stransky, P Ruth, M Schwab, MW Löffler - Cancers, 2021 - mdpi.com
Simple Summary Drug repurposing strategies utilize drugs, already approved by regulatory
authorities, to test their efficacy against different diseases. While this approach is …
authorities, to test their efficacy against different diseases. While this approach is …
Drug repurposing in oncology: a systematic review of randomized controlled clinical trials
I Ioakeim-Skoufa, N Tobajas-Ramos, E Menditto… - Cancers, 2023 - mdpi.com
Simple Summary Exploring the possibility of using well-known marketed drugs in new
therapeutic indications, commonly known as drug repurposing, offers certain advantages …
therapeutic indications, commonly known as drug repurposing, offers certain advantages …
Drug repurposing in cancer: now and beyond
AH Eid - Current Medicinal Chemistry, 2021 - ingentaconnect.com
Drug repurposing, also called drug repositioning, is an attractive approach that seeks to
identify new targets or treatments for existing drugs. This approach saves not only significant …
identify new targets or treatments for existing drugs. This approach saves not only significant …
“Hard” drug repurposing for precision oncology: the missing link?
P Pantziarka, G Bouche, N André - Frontiers in Pharmacology, 2018 - frontiersin.org
Drug repurposing is at the heart of precision oncology. The move from tissue-or cancer-
specific treatments to genomic-or actionable-target treatments necessarily entails the reuse …
specific treatments to genomic-or actionable-target treatments necessarily entails the reuse …