Exposure to stressful events can be differently perceived by individuals and can have
persistent sequelae depending on the level of stress resilience or vulnerability of each …

There is significant variation in the way individuals react and respond to extreme stress and
adversity. While some individuals develop psychiatric conditions such as posttraumatic …

Stress responses entail neuroendocrine, autonomic, and behavioral changes to promote
effective coping with real or perceived threats to one's safety. While these responses are …

Highlights•Individuals differ in the perception and adaptation to aversive and stressful
stimuli.•Stress-susceptibility is associated with functional changes in specific neural …

Humans exhibit a remarkable degree of resilience in the face of extreme stress, with most
resisting the development of neuropsychiatric disorders. Over the past 5 years, there has …

Research into the molecular basis of stress resilience is a novel strategy to identify potential
therapeutic strategies to treat stress-induced psychopathologies such as anxiety and …

Over the last 50 years, the concept of stress has evolved significantly, and our
understanding of the underlying neurobiology has expanded dramatically. Rather than …

Viable new treatments for depression and anxiety have been slow to emerge, likely owing to
the complex and incompletely understood etiology of these disorders. A budding area of …

The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

Stressful experiences, both physical and psychological, that are overwhelming (ie,
inescapable and unpredictable), can measurably affect subsequent neuronal properties and …