Intrathecal synthesis of IgM in neurological diseases: a comparison between detection of oligoclonal bands and quantitative estimation

MK Sharief, G Keir, EJ Thompson - Journal of the neurological sciences, 1990 - Elsevier
Immunoglobulin (Ig) M concentration in cerebrospinal fluid (CSF) was measured in 30
reference subjects to determine reference ranges which were up to 0.41 mg/l for CSF IgM …

The concentration of IgM in the cerebrospinal fluid of neurological patients

CJM Sindic, CL Cambiaso, A Depre, EC Laterre… - Journal of the …, 1982 - Elsevier
The level of IgM was determined by Particle Counting Immunoassay in the cerebrospinal
fluid. In non-neurological patients (N= 20) the mean was 97.5 μg/l with the upper reference …

The cerebrospinal fluid in multiple sclerosis. Quantitative assessment of intrathecal immunoglobulin synthesis by empirical formulae

F Sellebjerg, M Christiansen… - European Journal of …, 1996 - Wiley Online Library
Intrathecal synthesis of IgG occurs in more than 90% of patients with clinically definite
multiple sclerosis. The prevalence and significance of intrathecal synthesis of IgA and IgM …

Intrathecal immunoglobulin M synthesis in multiple sclerosis: relationship with clinical and cerebrospinal fluid parameters

MK Sharief, EJ Thompson - Brain, 1991 - academic.oup.com
Intrathecal IgM synthesis was assessed through the detection of oligoclonal bands in
cerebrospinal fluid (CSF) and through calculation of IgM index values and total CSF IgM …

Intrathecal synthesis of IgG, IgA, IgM and IgD in untreated multiple sclerosis and controls

F Lolli, I Halawa, H Link - Acta neurologica scandinavica, 1989 - Wiley Online Library
The intrathecal production (ITP) of the immunoglobulins (Ig) G, A, M and D was examined in
untreated patients with multiple sclerosis (MS) and controls. Sensitive sandwich enzyme …

On cerebrospinal fluid immunoglobulin-G (IgG) quotients in multiple sclerosis and other diseases: A review and a new formula to estimate the amount of IgG …

W Tourtellotte - Journal of the neurological Sciences, 1970 - Elsevier
This review of the cerebrospinal fluid (CSF) changes in multiple sclerosis has brought
together relevant recent advances in CSF physiology and some aspects of the pathology of …

Occurrence of oligoclonal IgM bands in the cerebrospinal fluid of neurological patients: an immunoaffinity-mediated capillary blot study

CJM Sindic, P Monteyne, EC Laterre - Journal of the neurological sciences, 1994 - Elsevier
We developed a highly sensitive and specific immunoaffinity-mediated capillary blot
technique for the detection of oligoclonal IgM bands in CSF and sera from patients with …

Intrathecal synthesis of IgM and IgA in neurological diseases: comparison of two formulae with isoelectric focusing

R Kaiser, CH Lücking - Clinica chimica acta, 1993 - Elsevier
Abstract The intrathecal IgM and IgA immune response was studied by detecting oligoclonal
IgM and IgA bands in CSF and by determining both the IgM/IgA indices as well as the …

Intrathecal IgG synthesis in multiple sclerosis and other neurological diseases: a comparative evaluation by IgG-index and isoelectric focusing

M Poloni, B Rocchelli, R Scelsi, P Pinelli - Journal of Neurology, 1979 - Springer
Intrathecal IgG synthesis has been investigated by determining the IgG index and by
isoelectric focusing in 30 cases of definite multiple sclerosis, in 15 cases of probable …

Evaluation of IgG synthesis in the central nervous system

H Reiber - Progress in multiple sclerosis research, 1980 - Springer
The cerebrospinal fluid (CSF)/serum concentration ratios of IgG (y) and albumin (x) are used
as measures to characterize increased IgG levels in CSF. From a group of control patients …