We present a novel instrument to measure the spectral, angular, azimuthal, and polarization
dependence of light backscattered by living biological tissues, thus providing the most …

We report an in situ method of probing the structure of living epithelial cells, based on light
scattering spectroscopy with polarized light. The method makes it possible to distinguish …

We present a novel instrument for imaging the angular distributions of light backscattered by
biological cells and tissues. The intensities in different regions of the image are due to …

Light scattered from biological tissues can exhibit an inverse power law spectral component.
We develop a model based on the Born approximation and von Karman (self-affine) spatial …

We present a method for selective detection of size-dependent scattering characteristics of
epithelial cells in vivo based on polarized illumination and polarization sensitive detection of …

An understanding of the relationship between tissue structures and light scattering from
tissue will help facilitate the development and acceptance of noninvasive optical diagnostics …

Background Using optical techniques for tissue diagnostics (so-called 'optical biopsy') has
been a subject of extensive research for many years. Various groups have been exploring …

Recently, there has been a major thrust to understand biological processes at the
nanoscale. Optical microscopy has been exceedingly useful in imaging cell …

Introduction: Our group has been interested in applying advances in biomedical optics to
colorectal cancer risk stratification. Through a recent technological breakthrough, we have …

The gold standard in histopathology relies on manual investigation of stained tissue
biopsies. A sensitive and quantitative method for in situ tissue specimen inspection is highly …